Progesterone Impurity 58 CAS 2919563-38-3
| CAS No. | 2919563-38-3 |
| Molecular Formula | C22H30O2 |
| Molecular Weight | 326.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Progesterone Impurity 58 (C22H30O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Progesterone Impurity 58 (CAS 2919563-38-3) is a certified pharmaceutical impurity reference standard with the molecular formula C22H30O2 and a molecular weight of 326.47 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Progesterone Impurity 58 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H30O2 |
| Molecular Weight | 326.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
Related Progesterone Standards
- Progesterone Bisnoraldehyde Impurity (CAS 81201-82-3)
- Progesterone EP Impurity L (CAS 2257421-80-8)
- Progesterone Impurity 44 (CAS CATO-C4X-150244)
- Progesterone Impurity 48 (CAS 115387-31-0)
- Progesterone Impurity 49 (CAS 96790-16-8)
- Progesterone Impurity 61 (CAS CATO-C4X-150261)
- Progesterone Impurity 79 (CAS CATO-C4X-150279)
- Progesterone Impurity 98 (CAS 3946-26-7)
Recommended Standards
- Levonorgestrel EP Impurity S (CAS 176254-10-7)
- 2-(Dimethyl(3-(undec-10-enamido)propyl)ammonio)acetate (CAS 133798-12-6)
- Levonorgestrel EP Impurity T (CAS 14507-51-8)
- .beta.-Naphthyl laurate 6343-73-3 Beta-Naphthyl laurate Dodecanoic acid, 2-naphthalenyl ester Lauric acid, 2-naphthyl ester NSC-49742 NSC49742 (CAS 6343-73-3)
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- (2S)-2,3-dihydroxypropanal (S)-2,3-dihydroxypropanal 497-09-6 CHEBI:27975 L-(-)-glyceraldehyde L-2,3-Dihydroxypropanal L-2,3-Dihydroxypropionaldehyde L-Aldotriose L-Glycerose L-glyceraldehyde (CAS 497-09-6)
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