Methylprednisolone Hydrogen Succinate EP Impurity E CAS 2920-86-7
| CAS No. | 2920-86-7 |
| Molecular Formula | C25H32O8 |
| Molecular Weight | 460.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Methylprednisolone Hydrogen Succinate EP Impurity E (CAS 2920-86-7), a pharmacopoeial impurity reference standard (molecular formula C25H32O8, MW 460.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C25H32O8, Methylprednisolone Hydrogen Succinate EP Impurity E contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 460.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H32O8 |
| Molecular Weight | 460.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Methylprednisolone Standards
- Methylprednisolone Impurity 63 (CAS 7415-42-1)
- Methylprednisolone Impurity 73 (CAS CATO-C4X-191973)
- Methylprednisolone impurity 97 (CAS CATO-C4X-191997)
- Methylprednisolone Impurity 53 (CAS CATO-C4X-191953)
- Methylprednisolone Impurity 68 (CAS 86413-24-3)
- Methylprednisolone Impurity 91 (CAS 124106-96-3)
- Methylprednisolone impurity 83 (CAS CATO-C4X-191983)
- Methylprednisolone Impurity 1 (CAS CATO-C4X-19191)
Recommended Standards
- Hydrocortisone Impurity 61 (CAS CATO-C4X-140161)
- Hydrocortisone Impurity 60 (CAS CATO-C4X-140160)
- 6-Dehydrocortisol 21-Hydrogen Succinate (CAS CATO-C4X-140157)
- Vibegron Impurity 10 (CAS CATO-C4X-237610)
- Relebactam Impurity 50 (CAS CATO-C4X-214450)
- Fudosteine Impurity 24 (CAS CATO-C4X-144724)
- N-Nitroso Fentanyl EP Impurity D (CAS 1184873-14-0)
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- S-(2-Cyanoethyl) ethanethioate (CAS 119174-33-3)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
Why CATO?
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