Hydrocortisone Impurity 60 CAS CATO-C4X-140160
| CAS No. | CATO-C4X-140160 |
| Molecular Formula | C25H32O8 |
| Molecular Weight | 460.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Hydrocortisone Impurity 60 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Hydrocortisone Impurity 60 (CAS CATO-C4X-140160, C25H32O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C25H32O8, Hydrocortisone Impurity 60 contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 460.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Hydrocortisone Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H32O8 |
| Molecular Weight | 460.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Hydrocortisone Standards
- Hydrocortisone Impurity 01 (CAS 10215-75-5)
- Hydrocortisone impurity 40 (CAS 33767-18-9)
- Hydrocortisone Impurity 61 (CAS CATO-C4X-140161)
- Hydrocortisone 17-Propionate 21-Acetate (CAS 74050-20-7)
- Hydrocortisone Impurity 39 (CAS 3593-96-2)
- Hydrocortisone Impurity 32 (CAS 103242-89-3)
- Hydrocortisone Impurity 67 (CAS 146201-55-0)
- Hydrocortisone Impurity 75 (CAS 220489-73-6)
Recommended Standards
- 6-Dehydrocortisol 21-Hydrogen Succinate (CAS CATO-C4X-140157)
- Methylprednisolone Hydrogen Succinate EP Impurity E (CAS 2920-86-7)
- Picosulfate impurity 30 (CAS CATO-C4X-123730)
- Methylprednisolone Impurity 63 (CAS 7415-42-1)
- Deferasirox Impurity 26 (CAS 1688656-83-8)
- Nintedanib Impurity N10 (CAS 1139457-10-5)
- Mirabegron Impurity 142 (CAS CATO-C4X-1032142)
- 5-(3-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-1H-pyrazol-3-amine (CAS 1030622-14-0)
- Hydantoin Impurity 8 (CAS 7060-39-1)
- 2-Hydroxymethyl-3-benzylhydroxyl-6-(2'-nitro-1'-hydroxy)ethyl Pyridine (CAS 885520-76-3)
- Methyl 3-(4-((2,2,2-trifluoroethyl)sulfonamido)phenoxy)thiophene-2-carboxylate (CAS 882747-59-3)
- Formoterol Impurity 49 (CAS 14367-46-5)
- Diethyl (4-(1,3-dioxolan-2-yl)phenyl)phosphonate (CAS 85416-98-4)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
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