2-((5-Bromo-2-hydroxybenzylidene)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile CAS 294651-50-6
| CAS No. | 294651-50-6 |
| Molecular Formula | C16H13BrN2OS |
| Molecular Weight | 361.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((5-Bromo-2-hydroxybenzylidene)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile.
2-((5-Bromo-2-hydroxybenzylidene)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (CAS 294651-50-6) is a high-purity analytical reference standard with the molecular formula C16H13BrN2OS and a molecular weight of 361.26 g/mol.
Structurally, 2-((5-Bromo-2-hydroxybenzylidene)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (C16H13BrN2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 361.26 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((5-Bromo-2-hydroxybenzylidene)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13BrN2OS |
| Molecular Weight | 361.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
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Recommended Standards
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- 2,3,4-Trifluorobenzoic Acid (CAS 61079-72-9)
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- (E,E)-Ceftizoxime Impurity 67 (CAS CATO-C4X-179367)
- 1-(3-(tert-Butyl)-1H-pyrazol-5-yl)piperazine (CAS 1469010-33-0)
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- 1-(3-Fluoro-4-methoxyphenyl)-2-(methylthio)ethan-1-one (CAS 1178931-81-1)
- (E)-2-(2-(5-Bromothiophen-2-yl)vinyl)quinolin-8-ol (CAS 1818235-97-0)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
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