2,2-Difluoro-N-(4-methoxyphenyl)-2-(3-(trifluoromethyl)phenoxy)acetamide CAS 338792-07-7
| CAS No. | 338792-07-7 |
| Molecular Formula | C16H12F5NO3 |
| Molecular Weight | 361.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2,2-Difluoro-N-(4-methoxyphenyl)-2-(3-(trifluoromethyl)phenoxy)acetamide (C16H12F5NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 361.26 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2,2-Difluoro-N-(4-methoxyphenyl)-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 338792-07-7), a certified reference material (molecular formula C16H12F5NO3, MW 361.26 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,2-Difluoro-N-(4-methoxyphenyl)-2-(3-(trifluoromethyl)phenoxy)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12F5NO3 |
| Molecular Weight | 361.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2,6-Difluoro-N-(4-phenylpiperazine-1-carbonothioyl)benzamide (CAS 497060-84-1)
- (R)-1-(3-(1,1-Difluoro-2-methyl-2-((triethylsilyl)oxy)propyl)-2-fluorophenyl)ethan-1-amine (CAS 2765156-87-2)
- 2,7-Difluoro-8-((triisopropylsilyl)ethynyl)naphthalen-1-ol (CAS 2852767-37-2)
- 4-((2,6-Difluoro-4-propylphenyl)ethynyl)-4'-ethyl-1,1'-biphenyl (CAS 221526-78-9)
- 4,4-(5,5-Difluoro-[1,1-biphenyl]-3,3-diyl)dimorpholine (CAS 1704068-67-6)
- 4,4''-Difluoro-5'-(4-fluorophenyl)-1,1':3',1''-terphenyl (CAS 448-60-2)
- 2,6-difluoro-3-nitro-N-[2-(trifluoromethoxy)phenyl]benzamide (CAS 260552-99-6)
- 2,6-difluoro-3-nitro-N-[4-(1,2,3-thiadiazol-4-yl)phenyl]benzamide (CAS 260554-94-7)
Recommended Standards
- 2-((5-Bromo-2-hydroxybenzylidene)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (CAS 294651-50-6)
- 2-Bromo-N-(4,7-dimethylbenzo[d]thiazol-2-yl)benzamide (CAS 842118-12-1)
- 2-((4-Bromophenyl)thio)-1-(2-methylimidazo[1,2-a]pyridin-3-yl)ethan-1-one (CAS 478029-66-2)
- 2-Bromo-N-(5,7-dimethylbenzo[d]thiazol-2-yl)benzamide (CAS 912761-18-3)
- N-(3-aminophenyl)tetrahydrothiophene-3-carboxamide 1,1-dioxide (CAS 1171598-25-6)
- 2-Formylbenzene-1-sulfonyl chloride (CAS 21639-41-8)
- 2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-7'-carbonitrile (CAS 1203686-91-2)
- AB-001 (CAS 1345973-49-0)
- 4-Benzylpiperazine-1-carbothioamide (CAS 23111-81-1)
- (S)-2-((tert-Butoxycarbonyl)amino)-2-methylbutanoic acid (CAS 151171-11-8)
- 9022-96-2 Butyl alcohol, titanium(4+) salt, polymers 1-Butanol, titanium(4+) salt (4:1), homopolymer 1-Butanol, titanium(4+) salt, homopolymer Poly(di-n-butoxy titanoxane) Titanium tetrabutylate polymer (CAS 9022-96-2)
- Octahydro-1H-indole (CAS 4375-14-8)
- 5-Morpholino-1H-1,2,4-triazol-3-amine (CAS 51420-46-3)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com