Norepinephrine Impurity 57 CAS 29477-54-1
| CAS No. | 29477-54-1 |
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Norepinephrine Impurity 57 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Norepinephrine Impurity 57 (CAS 29477-54-1, C8H8O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H8O4, Norepinephrine Impurity 57 contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 168.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
Related Norepinephrine Standards
- Norepinephrine Impurity 54 (CAS CATO-C4X-151454)
- Norepinephrine Impurity 58 (CAS 408328-15-4)
- Norepinephrine impurity 147 (CAS CATO-C4X-1514147)
- Norepinephrine Impurity 27 (CAS 14309-96-7)
- Norepinephrine Impurity 127 (CAS 94593-04-1)
- Norepinephrine Impurity 20 (CAS 67896-55-3)
- Norepinephrine Impurity 31 (CAS 73660-93-2)
- Norepinephrine Impurity 18 (CAS CATO-C4X-151418)
Recommended Standards
- Benserazide Impurity 59 (CAS CATO-C4X-142759)
- Minoxidil Impurity 53 (CAS CATO-C4X-170053)
- Mesalazine EP Impurity J (CAS 112725-89-0)
- Minoxidil Impurity 59 (CAS CATO-C4X-170059)
- Iguratimod Impurity 22 (CAS CATO-C4X-182622)
- Fluorometholone Impurity 4 (CAS 110664-42-1)
- Ceftazidime EP Impurity B (CAS 97148-38-4)
- Calcipotriol Impurity 36 (CAS CATO-C4X-122236)
- (E)-1,2-Bis(pyridin-4-ylmethyl)diazene (CAS 191084-02-3)
- 5-(2-(Ethylthio)pyrimidin-4-yl)furan-2-carboxylic acid (CAS 1399662-76-0)
- Blonanserin Impurity 41 (CAS CATO-C4X-111041)
- 5-Amino-1-(2-ethoxyethyl)pyridin-2(1h)-one (CAS 1094919-45-5)
- N-nitrosyl-ammonium bromide (CAS CATO-C4X-1085102)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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