Norepinephrine Impurity 58 CAS 408328-15-4
| CAS No. | 408328-15-4 |
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Norepinephrine Impurity 58.
As a process- or degradation-related impurity, Norepinephrine Impurity 58 (CAS 408328-15-4, C8H8O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Norepinephrine Impurity 58 (C8H8O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Norepinephrine Impurity 58 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Related Norepinephrine Standards
- Norepinephrine Impurity 54 (CAS CATO-C4X-151454)
- Norepinephrine Impurity 57 (CAS 29477-54-1)
- Norepinephrine impurity 147 (CAS CATO-C4X-1514147)
- Norepinephrine Impurity 27 (CAS 14309-96-7)
- Norepinephrine Impurity 127 (CAS 94593-04-1)
- Norepinephrine Impurity 20 (CAS 67896-55-3)
- Norepinephrine Impurity 31 (CAS 73660-93-2)
- Norepinephrine Impurity 18 (CAS CATO-C4X-151418)
Recommended Standards
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- HIV (gp120) Antigenic Peptide (H-2982.0500) (CAS 198636-94-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com