N-(3-(trifluoromethyl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide CAS 294853-44-4
| CAS No. | 294853-44-4 |
| Molecular Formula | C16H12F3NO3 |
| Molecular Weight | 323.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(3-(trifluoromethyl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide (CAS 294853-44-4), molecular formula C16H12F3NO3 and molecular weight 323.27 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C16H12F3NO3, N-(3-(trifluoromethyl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 323.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures N-(3-(trifluoromethyl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12F3NO3 |
| Molecular Weight | 323.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-(4-(3-(Trifluoromethyl)phenoxy)but-2-yn-1-yl)furan-2-carboxamide (CAS 1421450-68-1)
- N-(2-(3-(Trifluoromethyl)-1H-pyrazol-1-yl)ethyl)benzofuran-2-carboxamide (CAS 1448026-99-0)
- 2-({[2-Methyl-3-(trifluoromethyl)phenyl]amino}carbonyl)benzoic acid (CAS 2197063-21-9)
- 7-(1-(3-(Trifluoromethyl)phenoxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 306979-68-0)
- N-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)benzamide (CAS 905432-74-8)
- ((2-(Trifluoromethyl)phenyl)sulfonyl)proline (CAS 1009665-11-5)
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Recommended Standards
- N-Methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benzenecarboximidamide (CAS 339027-55-3)
- 9-(4-Fluorophenyl)[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(6H)-one (CAS 861208-11-9)
- Varenicline Impurity 7 (CAS 357426-10-9)
- 1-(2-Fluorophenyl)-6-(furan-2-yl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011398-23-4)
- 4-Chloro-N'-methyl-N'-(4-methyl-3-(methylsulfonyl)-6-phenylpyridin-2-yl)benzohydrazide (CAS 303986-74-5)
- 2,2,2-Trifluoro-1-(2-fluoro-4-methoxyphenyl)ethan-1-ol (CAS 1247761-10-9)
- (2E)-N-(4-butylphenyl)-2-(hydroxyimino)acetamide (CAS 18331-68-5)
- 1-azido-2-fluorobenzene (CAS 3296-04-6)
- 7-Ethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1221723-15-4)
- (1R,3r)-3-hydroxy-1-(isopropoxycarbonyl)-3-methylcyclobutane-1-carboxylic acid (CAS 2137050-01-0)
- 3-(Quinolin-3-yl)acrylic acid (CAS 67752-27-6)
- Pioglitazone impurity 53 (CAS CATO-C4X-138353)
- 2,2,2-Trifluoro-1-(5-methyl-1H-pyrrol-2-yl)ethanone (CAS 18087-63-3)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
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