4-Chloro-N'-methyl-N'-(4-methyl-3-(methylsulfonyl)-6-phenylpyridin-2-yl)benzohydrazide CAS 303986-74-5
| CAS No. | 303986-74-5 |
| Molecular Formula | C21H20ClN3O3S |
| Molecular Weight | 429.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-N'-methyl-N'-(4-methyl-3-(methylsulfonyl)-6-phenylpyridin-2-yl)benzohydrazide (CAS 303986-74-5) is a high-purity analytical reference standard with the molecular formula C21H20ClN3O3S and a molecular weight of 429.92 g/mol.
The molecular framework of 4-Chloro-N'-methyl-N'-(4-methyl-3-(methylsulfonyl)-6-phenylpyridin-2-yl)benzohydrazide (C21H20ClN3O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H20ClN3O3S |
| Molecular Weight | 429.92 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-3-(N-(2,5-dimethylphenyl)sulfamoyl)-N-(pyridin-2-ylmethyl)benzamide (CAS 827013-98-9)
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- N-[5-Chloro-2-[(1E)-3-[(2R)-4-[(4-Fluorophenyl)Methyl]-2-Methyl-1-Piperazinyl]-3-Oxo-1-Propen-1-Yl]Phenyl]-Acetamide (CAS 685534-25-2)
- 9-(4''-Chloro-[1,1':4',1''-terphenyl]-4-yl)-9H-carbazole (CAS 1663490-99-0)
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Recommended Standards
- Methyl 4-[(n-benzyl4-chlorobenzenesulfonamido)methyl]benzoate (CAS 869775-77-9)
- N-(3-(4-Chlorophenyl)allyl)-N-(2-(isoquinoline-5-sulfonamido)ethyl)formamide (CAS 130964-32-8)
- N-Benzyl-4-chloro-N-{[4-(hydrazinecarbonyl)phenyl]methyl}benzene-1-sulfonamide (CAS 721416-43-9)
- 4-(Thiazolidin-2-yl)phenol (CAS 31404-07-6)
- Ethyl 2-(imidazo[1,2-a]pyridin-3-yl)acetate (CAS 101820-69-3)
- Caulophyllumine A (CAS 1009318-60-8)
- 2-(3,3-Difluoropiperidin-1-yl)ethan-1-amine (CAS 1228631-24-0)
- D-Ascorbic Acid Impurity 19 (CAS 67776-07-2)
- 1-Isobutyl-1h-1,2,4-triazol-3-amine (CAS 1183673-76-8)
- 5-Chloro-2-methoxy-9-phenoxyacridine (CAS 94551-44-7)
- 4-Bromo-1,3-dimethyl-1H-pyrazol-5-amine hydrobromide (CAS 1431965-46-6)
- [2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine (CAS 1868-85-5)
- Tamsulosin Impurity 51 (CAS CATO-C4X-118751)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
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