Metformin EP Impurity B Hydrochloride CAS 2959-04-8
| CAS No. | 2959-04-8 |
| Molecular Formula | C4H8N8 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Metformin EP Impurity B Hydrochloride (CAS 2959-04-8), a pharmacopoeial impurity reference standard (molecular formula C4H8N8HCl, MW 204.62 g/mol) used for the identification and quantification of trace impurities in APIs.
Metformin EP Impurity B Hydrochloride (C4H8N8HCl) contains a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Metformin EP Impurity B Hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H8N8 HCl |
| Molecular Weight | 204.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Metformin Standards
- Metformin EP Impurity D (CAS 108-78-1)
- Metformin Hydrochloride (CAS 1115-70-4)
- Metformin-d6 Hydrochloride (CAS 1185166-01-1)
- Metformin Impurity 38 (CAS 118632-64-7)
- Metformin EP impurity F Tetrahydrofuran Solution (CAS 124-40-3 (free base))
- Metformin Impurity 532 (CAS 141-83-3)
- Metformin Impurity N74 (CAS 1609-00-3)
- Metformin EP Impurity E HCl (CAS 1674-62-0)
Recommended Standards
- CAS CATO-C3D-262790 (CAS CATO-C3D-262790)
- Olodaterol Impurity 12 (CAS CATO-C4X-194312)
- Teneligliptin Impurity 5 (CAS 1415908-67-6)
- Dimethyl 1H-pyrrole-2,4-dicarboxylate (CAS 2818-07-7)
- 6-Methyl-3-phenylpyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione (CAS 42285-76-7)
- N4-(3,4-Dimethylphenyl)-N2-methylpteridine-2,4-diamine (CAS 946297-63-8)
- 5-Fluoroisoquinolin-3-ol (CAS 1822915-46-7)
- 3-Amino-2,2-dimethylpropanol (CAS 26734-09-8)
- N-(3-iodophenyl)thietan-3-amine (CAS 1864717-46-3)
- Tirzepatide Impurity 36 (CAS CATO-C4X-324036)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com