Dexamethasone Acid Ethyl Ester CAS 2991360-83-7
| CAS No. | 2991360-83-7 |
| Molecular Formula | C23H31FO5 |
| Molecular Weight | 406.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Dexamethasone Acid Ethyl Ester (CAS 2991360-83-7) is a certified pharmaceutical impurity reference standard with the molecular formula C23H31FO5 and a molecular weight of 406.49 g/mol.
Structurally, Dexamethasone Acid Ethyl Ester (C23H31FO5) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 406.49 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H31FO5 |
| Molecular Weight | 406.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity N1 (CAS 37926-77-5)
- Dexamethasone 17-Formyloxy-17-Acid (CAS 473273-04-0)
- Dexamethasone Impurity 61 (CAS CATO-C4X-116561)
- Dexamethasone Impurity 96 (CAS 84449-15-0)
- Dexamethasone Impurity 24 (CAS 55879-47-5)
- Dexamethasone Impurity 97 (CAS CATO-C4X-116597)
- Dexamethasone Impurity 24 (CAS 24510-54-1)
- Dexamethasone EP Impurity B Hydrochloride (CAS 956901-32-9)
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