Dexamethasone Impurity 24 CAS 55879-47-5
| CAS No. | 55879-47-5 |
| Molecular Formula | C22H29FO6 |
| Molecular Weight | 408.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Dexamethasone Impurity 24 (C22H29FO6) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 408.46 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Dexamethasone Impurity 24 (CAS 55879-47-5) is a certified pharmaceutical impurity reference standard with the molecular formula C22H29FO6 and a molecular weight of 408.46 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H29FO6 |
| Molecular Weight | 408.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 97 (CAS CATO-C4X-116597)
- Dexamethasone Acid Ethyl Ester (CAS 2991360-83-7)
- Dexamethasone Impurity N1 (CAS 37926-77-5)
- Dexamethasone 17-Formyloxy-17-Acid (CAS 473273-04-0)
- Dexamethasone Impurity 61 (CAS CATO-C4X-116561)
- Dexamethasone Impurity 96 (CAS 84449-15-0)
- Dexamethasone Acetate EP Impurity F (CAS 2884-51-7)
- Dexamethasone Impurity 24 (CAS 24510-54-1)
Recommended Standards
- 6-Hydroxy Betamethasone (CAS 24703-00-2)
- 3-(((3-(Trifluoromethyl)benzyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one (CAS 477860-29-0)
- Betamethasone impurity 51 (CAS 1184871-61-1)
- 3-[(1R)-2-(Dimethylamino)-1-methylethoxy]-5-[[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino]-2-pyrazinecarbonitrile (CAS 1404095-34-6)
- Baricitinib Impurity 102 (CAS CATO-C4X-2260102)
- Edoxaban Impurity 84 (CAS CATO-C4X-106384)
- Olaparib Impurity 21 (CAS CATO-C4X-1135121)
- 6-(Thiomorpholin-4-yl)pyridin-3-amine (CAS 471938-15-5)
- 2-(Difluoromethyl)-6-(trifluoromethoxy)phenol (CAS 1261778-45-3)
- 2-(4-Bromophenyl)-6-chloroquinoline-4-carbonyl chloride (CAS 1160263-28-4)
- Nilotinib Impurity 45 (CAS CATO-C4X-125645)
- Bevirimat (CAS 174022-42-5)
- N'-(4-methylbenzoyl)quinoline-6-carbohydrazide (CAS 900018-77-1)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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