Tofacitinib Impurity 249 CAS CATO-C4X-1079249

Description

Compared with other compounds in its class, the molecular weight of 345.87 g/mol gives Tofacitinib Impurity 249 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Tofacitinib Impurity 249 (CAS CATO-C4X-1079249), a pharmacopoeial impurity reference standard (molecular formula C18H24ClN5, MW 345.87 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Tofacitinib Impurity 249 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 345.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Tofacitinib Impurity 249 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
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• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com