2-(4-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one CAS 299897-98-6
| CAS No. | 299897-98-6 |
| Molecular Formula | C18H16ClN3O |
| Molecular Weight | 325.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(4-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one (C18H16ClN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-(4-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one (CAS 299897-98-6), a certified reference material (molecular formula C18H16ClN3O, MW 325.79 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(4-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16ClN3O |
| Molecular Weight | 325.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- (4Z)-4-({[(4-chlorophenyl)methyl]amino}methylidene)-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one (CAS 320425-10-3)
- 1-Benzyl-3-[(4-chlorophenyl)methyl]-4-hydroxy-1,2-dihydropyridin-2-one (CAS 477846-41-6)
- 2-(3-Chlorophenyl)-3,6,8-trimethylquinoline-4-carboxylic acid (CAS 895965-50-1)
- 2-(3-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one (CAS 299898-01-4)
- 2-(4-Chlorophenyl)-3,6,8-trimethylquinoline-4-carboxylic acid (CAS 895923-44-1)
- 3-(5-(3-Chlorophenyl)furan-2-yl)-N-phenylpropanamide (CAS 853312-43-3)
- 3-(5-(4-Chlorophenyl)furan-2-yl)-N-phenylpropanamide (CAS 853311-43-0)
- 4-((2-Chlorophenyl)amino)-2-(4-methylpiperazin-1-yl)-4-oxobutanoic acid (CAS 540763-74-4)
Recommended Standards
- 2-(5-Chloro-8-isopropoxyquinolin-7-yl)benzaldehyde (CAS 648897-06-7)
- 2-Benzyl-4-(benzylamino)-5-chloropyridazin-3(2H)-one (CAS 91736-90-2)
- 2-Chloro-3-((4-isopropylphenyl)amino)naphthalene-1,4-dione (CAS 763130-56-9)
- 2-Chloro-n-[3-(4-methylphenyl)-1-phenyl-1h-pyrazol-5-yl]acetamide (CAS 956262-31-0)
- 2,4-Dichloro-6-(6-chlorooxazolo[5,4-b]pyridin-2-yl)aniline (CAS 1354778-24-7)
- Butyric acid-d7 (CAS 73607-83-7)
- Isopropyl 1-methyl-1H-pyrazole-4-carboxylate (CAS 1429418-36-9)
- N1-Isopropyl-N2-(3-methyl-4-(2-oxopyrrolidin-1-yl)phenyl)oxalamide (CAS 941890-32-0)
- 2-(((2-Bromopyridin-4-yl)methyl)(cyclopropyl)amino)acetic acid (CAS 1353952-72-3)
- Ethyl 8-cyclopropyl-8-oxooctanoate (CAS 898776-36-8)
- 2,2,2-Trifluoro-1-(2-isopropylphenyl)ethan-1-amine (CAS 886369-11-5)
- 3-[4-(4-Methoxyphenyl)piperazin-1-yl]-1-(naphthalen-2-yl)propan-1-ol (CAS 477328-90-8)
- 2-Ethylbenzene-1,3-diol (CAS 4074-50-4)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
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