4-(5-Fluoro-1,3-dioxoisoindolin-2-yl)benzoic acid CAS 299963-58-9
| CAS No. | 299963-58-9 |
| Molecular Formula | C15H8FNO4 |
| Molecular Weight | 285.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 285.23 g/mol gives 4-(5-Fluoro-1,3-dioxoisoindolin-2-yl)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-(5-Fluoro-1,3-dioxoisoindolin-2-yl)benzoic acid (CAS 299963-58-9), a certified reference material (molecular formula C15H8FNO4, MW 285.23 g/mol) for analytical method development and quality control.
The molecular framework of 4-(5-Fluoro-1,3-dioxoisoindolin-2-yl)benzoic acid (C15H8FNO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(5-Fluoro-1,3-dioxoisoindolin-2-yl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H8FNO4 |
| Molecular Weight | 285.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 2-(5-Fluoro-1,3-dioxoisoindolin-2-yl)benzoic acid (CAS 299963-55-6)
- (3-Fluoro-3'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)methanamine (CAS 1261836-76-3)
- 6-Fluoro-2-(4-fluorophenyl)quinoline-4-carboxylic acid (CAS 1543-31-3)
- 1-(4-Fluoro-3-(trifluoromethyl)phenyl)-4-oxocyclohexanecarbonitrile (CAS 1956334-20-5)
- (3-Fluoro-4'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)methanamine (CAS 472964-41-3)
- 4-Fluoro-2,5-bis(2-fluorophenyl)pyridine (CAS 1214384-67-4)
- 7-Fluoro-2-(trifluoromethyl)-10H-phenothiazine (CAS 55389-09-8)
- N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide (CAS 606132-13-2)
Recommended Standards
- 5-(2-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole (CAS 693236-20-3)
- 2-(3-Fluorophenyl)-1,3-dioxoisoindoline-5-carboxylic acid (CAS 202264-03-7)
- 5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole (CAS 421581-70-6)
- 1,3-Dioxoisoindolin-2-yl 4-fluorobenzoate (CAS 305359-06-2)
- 1-(Benzo[c][1,2,5]thiadiazol-4-ylsulfonyl)piperidine-3-carboxylic acid (CAS 1119451-24-9)
- Methyl 3-amino-5-(ethylthio)-4H-1,2,4-triazole-4-carboxylate (CAS 79742-00-0)
- 1-[(4-fluorophenyl)methyl]cyclopropan-1-ol (CAS 1251262-92-6)
- 3-Isobutyl-1-methyl-d (CAS 1219805-28-3)
- (2R,6R)-2,6-Dimethylpiperidine (CAS 14231-78-8)
- 4-(5-Methylpyridin-2-yl)benzaldehyde (CAS 1008744-15-7)
- 5-((4-Carboxyphenoxy)methyl)isophthalic acid (CAS 2115107-14-5)
- Prednisolone impurity 64 (CAS 50557-66-9)
- (1R,4S,6S)-rel-tert-Butyl 6-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 198835-05-1)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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