1-Ethyl-4-hydroxy-N-(4-iodophenyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide CAS 300716-33-0
| CAS No. | 300716-33-0 |
| Molecular Formula | C18H15IN2O3 |
| Molecular Weight | 434.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Ethyl-4-hydroxy-N-(4-iodophenyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide.
1-Ethyl-4-hydroxy-N-(4-iodophenyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide (CAS 300716-33-0), molecular formula C18H15IN2O3 and molecular weight 434.23 g/mol, is a CATO reference standard with documented purity and traceability.
1-Ethyl-4-hydroxy-N-(4-iodophenyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide (C18H15IN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Ethyl-4-hydroxy-N-(4-iodophenyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15IN2O3 |
| Molecular Weight | 434.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- N-(4-(4-(Bis(2-chloroethyl)amino)phenoxy)butyl)acridin-9-amine (CAS 130031-47-9)
- 1-Cyclobutylprop-2-en-1-one (CAS 75040-32-3)
- 1-Methyl-3-(trifluoromethyl)-1H-pyrazole (CAS 154471-65-5)
- 2,3-Pentanedione (CAS 600-14-6)
- 2,6-Dimethoxy-4-pyridinemethanol (CAS 52606-06-1)
- 2-Methylquinolin-8-yl (3-chlorophenyl)carbamate (CAS 14577-78-7)
- 6-Methoxy-2-methyl-2,3,4,5-tetrahydropyridine (CAS 61586-88-7)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
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