(E)-2-(3,5-Dimethoxystyryl)-6-iodoquinazolin-4(3H)-one CAS 922189-13-7
| CAS No. | 922189-13-7 |
| Molecular Formula | C18H15IN2O3 |
| Molecular Weight | 434.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-2-(3,5-Dimethoxystyryl)-6-iodoquinazolin-4(3H)-one (CAS 922189-13-7), molecular formula C18H15IN2O3 and molecular weight 434.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-2-(3,5-Dimethoxystyryl)-6-iodoquinazolin-4(3H)-one (C18H15IN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-2-(3,5-Dimethoxystyryl)-6-iodoquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H15IN2O3 |
| Molecular Weight | 434.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- (E)-2-(3,4-Dimethoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine (CAS 42880-07-9)
- 2-(3,4-Dimethoxystyryl)-6-hydroxy-5-nitropyrimidin-4(3H)-one (CAS 797778-69-9)
- (E)-4-(3,5-Dimethoxystyryl)-1,2-dimethoxybenzene (CAS 83088-26-0)
- 4-(3,5-Dimethoxystyryl)-1,2-dimethoxybenzene (CAS 20767-18-4)
- (Z)-6-(3,5-Dimethoxystyryl)benzofuran-4-ol (CAS 832128-21-9)
- (E)-2-(3,5-Dimethoxystyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1073354-86-5)
- 6-(3,4-Dimethoxystyryl)-4-methoxy-2H-pyran-2-one (CAS 2743-14-8)
- (E)-5-(3,5-Dimethoxystyryl)-2-methoxyphenol (CAS 108957-73-9)
Recommended Standards
- N-(4-(N-(2-Fluoro-4-iodophenyl)sulfamoyl)phenyl)acetamide (CAS 1421261-99-5)
- 1-Ethyl-4-hydroxy-N-(4-iodophenyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide (CAS 300716-33-0)
- 1,3-Bis[(4-bromophenyl)sulfanyl]propan-2-ol (CAS 400081-04-1)
- N-Allyl-2-((3,4-dichlorophenyl)amino)-6-nitro-4-oxo-3,4-dihydroquinazoline-8-carboxamide (CAS 331645-84-2)
- 3-Bromo-5-chloro-2-methoxyaniline (CAS 7270-83-9)
- 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 1165935-87-4)
- (6-Methylbenzo[d]oxazol-2-yl)methanamine hydrochloride (CAS 1158477-80-5)
- 6-Formamido-1,2,4-triazine-5-carboxamide (CAS 19359-68-3)
- 3-methyl-1-propyl-1H-pyrazol-4-amine,HCl (CAS 1197228-06-0)
- 2-Fluoro-3-methoxypyridine-4-boronic acid (CAS 1451392-01-0)
- 3-(4-Chlorophenyl)pyrimidin-4(3H)-one (CAS 109853-43-2)
- 2-((1-Benzyl-4-methyl-1H-pyrazol-3-yl)oxy)-2-methylpropanoic acid (CAS 68430-08-0)
- (2-Methylthiophen-3-yl)(naphthalen-1-yl)methanol (CAS 1443310-29-9)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com