2-Chloro-4-fluorophenyl acetate CAS 301653-18-9
| CAS No. | 301653-18-9 |
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-4-fluorophenyl acetate is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Chloro-4-fluorophenyl acetate (CAS 301653-18-9) is a high-purity analytical reference standard with the molecular formula C8H6ClFO2 and a molecular weight of 188.58 g/mol.
The molecular framework of 2-Chloro-4-fluorophenyl acetate (C8H6ClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-4-fluorophenyl acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
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- 2-Chloro-3-fluoro-4-methoxybenzaldehyde (CAS 1002344-90-2)
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Recommended Standards
- 2-Chloro-4-fluoro-5-methylbenzoic acid (CAS 208165-96-2)
- 2-chloro-6-(trifluoromethyl)pyrazine (CAS 61655-69-4)
- 2-Chloro-4-fluoro-3-methoxybenzaldehyde (CAS 750586-10-8)
- 2-Chloro-6-fluoro-3-methylbenzoic Acid (CAS 32890-89-4)
- 3-(1-(2-Methoxyethyl)-2,5-dimethyl-1H-pyrrol-3-yl)-3-oxopropanenitrile (CAS 1403564-18-0)
- 1-(3,4-Diaminophenyl)-2-morpholinoethan-1-one (CAS 1215969-52-0)
- Methyl (1R,2R)-2-phenylcyclobutane-1-carboxylate (CAS 50302-82-4)
- 2-(3,4-Dihydroxyphenyl)-3-hydroxy-6-propyl-4H-chromen-4-one (CAS 1313738-79-2)
- 2-Vinylnaphthalene (CAS 827-54-3)
- 0432AD 1-(3-Amino-phenoxy)-3-(2-methyl-benzoimidazol-1-yl)-propan-2-ol dihydrochloride 1185301-37-4 C17H21Cl2N3O2 (CAS 1185301-37-4)
- 6-Chloro-4-cyanopicolinic acid (CAS 1060809-92-8)
- n-(1-Methoxypropan-2-yl)-3-methylcyclopentan-1-amine (CAS 1339164-87-2)
- 4-Fluoro-N-(3-fluoro-4-methylphenyl)benzamide (CAS 356086-18-5)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
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