Diltiazem impurity 29 CAS 30193-56-7
| CAS No. | 30193-56-7 |
| Molecular Formula | C17H19NO4S |
| Molecular Weight | 333.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Diltiazem impurity 29 is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Diltiazem impurity 29 (CAS 30193-56-7, C17H19NO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Diltiazem impurity 29 (C17H19NO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H19NO4S |
| Molecular Weight | 333.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Diltiazem Standards
- Diltiazem Impurity 15 (CAS CATO-C4X-136815)
- Diltiazem Impurity 32 (CAS CATO-C4X-136832)
- Diltiazem Impurity 7 (CAS CATO-C4X-13687)
- Diltiazem EP Impurity B (CAS 87447-47-0)
- Diltiazem Impurity N1 (CAS 42399-48-4)
- Diltiazem Impurity N2 (CAS 42399-50-8)
- Diltiazem Impurity 18 (CAS 131613-02-0)
- Diltiazem Impurity 23 (CAS 119009-50-6)
Recommended Standards
- Febuxostat Impurity 94 (CAS CATO-C4X-116294)
- Febuxostat Impurity 85 (CAS CATO-C4X-116285)
- Lovastatin Impurity 46 (CAS CATO-C4X-168446)
- TG3-95-1 (CAS 301322-12-3)
- Faropenem Impurity 26 (CAS CATO-C4X-128926)
- Doripenem Impurity 17 (CAS 90776-59-3)
- Metoclopramide Impurity 42 (CAS 163082-23-3)
- 7-Ethoxyquinoline-3-carbaldehyde (CAS 745830-19-7)
- N-Butylphthalimide (CAS 1515-72-6)
- N-(tert-Butyl)nicotinamide (CAS 15828-08-7)
- 4-((Benzyloxy)methyl)-6-chloropyrimidine (CAS 914802-11-2)
- tert-Butyl N-[4-(Aminomethyl)-1-benzylpiperidin-4-yl]carbamate (CAS 1392491-65-4)
- (2s)-1,1,1-Trifluoro-3,3-dimethylbutan-2-amine hydrochloride (CAS 336105-51-2)
- (Cys2)-Neuropeptide Y-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32) (H-3298.0500) (CAS 128806-04-2)
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