Diltiazem EP Impurity B CAS 87447-47-0
| CAS No. | 87447-47-0 |
| Molecular Formula | C18H17NO4S |
| Molecular Weight | 343.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Diltiazem EP Impurity B (CAS 87447-47-0), a pharmacopoeial impurity reference standard (molecular formula C18H17NO4S, MW 343.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H17NO4S, Diltiazem EP Impurity B contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 343.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Diltiazem EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17NO4S |
| Molecular Weight | 343.40 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Diltiazem Standards
- Diltiazem Impurity 15 (CAS CATO-C4X-136815)
- Diltiazem impurity 29 (CAS 30193-56-7)
- Diltiazem Impurity 32 (CAS CATO-C4X-136832)
- Diltiazem Impurity 7 (CAS CATO-C4X-13687)
- Diltiazem Impurity 7 (CAS 84903-82-2)
- Diltiazem Impurity 11 (CAS 81353-09-5)
- Diltiazem Impurity 24 (CAS CATO-C4X-136824)
- Diltiazem Impurity N1 (CAS 42399-48-4)
Recommended Standards
- Faropenem Impurity 76 (CAS CATO-C4X-128976)
- N1-Nitroso Ranitidine (CAS CATO-C4X-137026)
- Ceftazidime Impurity 47 (CAS 199923-06-3)
- N2-Nitroso Ranitidine (CAS CATO-C4X-137027)
- Warfarin Impurity 14 (CAS 464921-27-5)
- Fluorescein Impurity 5 (CAS 7262-41-1)
- Azilsartan Impurity 16 (CAS 632322-61-3)
- Z-Arg-Leu-Arg-Gly-Gly-AMC (CAS 167698-69-3)
- 2-(Methylsulfonyl)-3,5-diphenylpyrimidin-4(3H)-one (CAS 1253786-30-9)
- Tert-butyl 4-(N-methylacetamido)piperidine-1-carboxylate (CAS 197727-57-4)
- Lifitegrast Impurity 82 (CAS CATO-C4X-240982)
- 4-Bromo-5-chloroquinoline (CAS 1629614-42-1)
- 1-Aminopiperidine HCl (CAS 63234-70-8)
- Peptide Impurity 27 (CAS 1350456-68-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com