Diltiazem Impurity N1 CAS 42399-48-4
| CAS No. | 42399-48-4 |
| Molecular Formula | C16H17NO4S |
| Molecular Weight | 319.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Diltiazem Impurity N1 (CAS 42399-48-4, C16H17NO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Diltiazem Impurity N1 (C16H17NO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 319.38 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Diltiazem Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H17NO4S |
| Molecular Weight | 319.38 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Diltiazem Standards
- Diltiazem Impurity N2 (CAS 42399-50-8)
- Diltiazem Impurity 18 (CAS 131613-02-0)
- Diltiazem Impurity 23 (CAS 119009-50-6)
- Diltiazem Impurity 33 (CAS CATO-C4X-136833)
- Diltiazem Impurity 15 (CAS CATO-C4X-136815)
- Diltiazem impurity 29 (CAS 30193-56-7)
- Diltiazem Impurity 32 (CAS CATO-C4X-136832)
- Diltiazem Impurity 7 (CAS CATO-C4X-13687)
Recommended Standards
- Dicyclohexyl(4-nitrophenyl)phosphine (CAS 40438-56-0)
- 6-Methyl-5-phenyl-2-(pyridin-2-yl)thieno[2,3-d]pyrimidin-4(3H)-one (CAS 724746-07-0)
- Ethyl (4-(2-(benzylamino)-2-oxoethyl)thiazol-2-yl)carbamate (CAS 946236-61-9)
- 6-Methoxy-2,3-dimethylbenzoic acid (CAS 5628-64-8)
- Ketoconazole Impurity 15 (CAS 581806-59-9)
- Pitolisant Impurity 45 (CAS CATO-C4X-252045)
- Cefcapene Impurity 90 Disodium Salt (CAS 28242-91-3 (free acid))
- Phthalazine-1-carboxamide (CAS 170940-78-0)
- 2-(cyclopropylamino)-2-(2,6-difluorophenyl)acetic acid (CAS 1218402-52-8)
- 1,5-Dibromo-2-difluoromethoxy-4-fluorobenzene (CAS 1804515-34-1)
- Fulvestrant impurity 46 (CAS CATO-C4X-191746)
- Methyl 3-chloro-6-morpholin-4-ylpyridine-2-carboxylate (CAS 1256806-14-0)
- Methyl 5-formyl-4-methylpicolinate (CAS 1263060-77-0)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com