N-(4-Bromophenyl)-1-butyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide CAS 303093-29-0
| CAS No. | 303093-29-0 |
| Molecular Formula | C20H19BrN2O3 |
| Molecular Weight | 415.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-Bromophenyl)-1-butyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide (C20H19BrN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies N-(4-Bromophenyl)-1-butyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide (CAS 303093-29-0), a certified reference material (molecular formula C20H19BrN2O3, MW 415.28 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H19BrN2O3 |
| Molecular Weight | 415.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 4-(4-Bromophenyl)-2-{[2-(1H-indol-2-yl)ethyl]amino}-4-oxobutanoic acid (CAS 1024591-91-0)
- 4-(5-(4-Bromophenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)-4-oxobutanoic acid (CAS 309926-09-8)
- N-(2-Bromophenyl)-1-butyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide (CAS 303093-27-8)
- (3E)-3-{[(2-bromophenyl)methoxy]imino}-1-(2-phenyl-1,3-thiazol-5-yl)propan-1-one (CAS 338414-42-9)
- {2-[(4-bromophenyl)sulfanyl]pyridin-3-yl}methyl N-phenylcarbamate (CAS 478031-10-6)
- 2-(4-bromophenyl)-2-oxoethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate (CAS 1795506-99-8)
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Recommended Standards
- Eltrombopag Impurity 106 (CAS CATO-C4X-1198106)
- 2-({[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]amino}methylidene)-2,3-dihydro-1H-indene-1,3-dione (CAS 1023531-54-5)
- 1-(Tert-butyl) 3-methyl (3S,4S)-4-(5-bromo-3-methoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylate (CAS 1217743-30-0)
- (2Z)-2,3-Dichloro-N-(6-methoxypyridin-3-yl)-3-[(4-methylphenyl)methanesulfonyl]prop-2-enamide (CAS 1164529-74-1)
- (3-Methoxy-5-methylphenyl)boronic acid (CAS 725251-81-0)
- Methyl 5-((3-chloro-4-methylphenyl)carbamoyl)-2-(3-methoxybenzamido)-4-methylthiophene-3-carboxylate (CAS 332923-77-0)
- (E)-1-Nitro-4-(2-nitrovinyl)benzene (CAS 5576-98-7)
- tert-Butyl (6-aminobenzo[d]thiazol-2-yl)carbamate (CAS 862822-07-9)
- N-Vinylbenzamide (CAS 13313-25-2)
- 5-(1,3-dimethyl-1h-pyraZol-4-yl)isoxazole (CAS 1005553-66-1)
- Rivastigmine Impurity 19 (CAS CATO-C4X-138419)
- 3-{[(3,4-dichlorophenyl)methyl]amino}propan-1-ol hydrochloride (CAS 1135064-72-0)
- 7-Fluoropyrido[4,3-d]pyrimidin-4(1H)-one (CAS 171178-37-3)
- Calcium-Like Peptide 3 (CAS 261969-05-5)
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