Eltrombopag Impurity 106 CAS CATO-C4X-1198106
| CAS No. | CATO-C4X-1198106 |
| Molecular Formula | C19H19BrN4O2 |
| Molecular Weight | 415.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C19H19BrN4O2, Eltrombopag Impurity 106 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 415.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Eltrombopag Impurity 106 (CAS CATO-C4X-1198106) is a certified pharmaceutical impurity reference standard with the molecular formula C19H19BrN4O2 and a molecular weight of 415.28 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Eltrombopag Impurity 106 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H19BrN4O2 |
| Molecular Weight | 415.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Eltrombopag Standards
- Eltrombopag impurity 149 (CAS CATO-C4X-1198149)
- Eltrombopag impurity 147 (CAS CATO-C4X-1198147)
- Eltrombopag Impurity 103 (CAS CATO-C4X-1198103)
- Eltrombopag Impurity 73 (CAS CATO-C4X-119873)
- Eltrombopag Impurity 133 (CAS CATO-C4X-1198133)
- Eltrombopag Impurity 134 (CAS CATO-C4X-1198134)
- Eltrombopag Impurity 71 (CAS CATO-C4X-119871)
- Eltrombopag Impurity 108 (CAS CATO-C4X-1198108)
Recommended Standards
- N-(4-Bromophenyl)-1-butyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide (CAS 303093-29-0)
- 2-({[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]amino}methylidene)-2,3-dihydro-1H-indene-1,3-dione (CAS 1023531-54-5)
- N-(2-Bromophenyl)-1-butyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide (CAS 303093-27-8)
- (2Z)-2,3-Dichloro-N-(6-methoxypyridin-3-yl)-3-[(4-methylphenyl)methanesulfonyl]prop-2-enamide (CAS 1164529-74-1)
- Isosulfan Blue impurity 6 (CAS CATO-C4X-30456)
- Cefuroxime Sodium Impurity 29 (CAS CATO-C4X-124529)
- Deoxycholic acid Impurity 41 (CAS CATO-C4X-335941)
- 6-(Trifluoromethyl)picolinohydrazide (CAS 883037-22-7)
- Ethyl 2-((7-bromo-1H-indol-3-yl)thio)acetate (CAS 2675450-16-3)
- 1-(Amino(4-bromophenyl)methyl)naphthalen-2-ol hydrochloride (CAS 1170560-78-7)
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-(3-fluoro-phenoxy)-2-pyrrolidinecarboxylic acid (CAS 869681-96-9)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,8-naphthyridine (CAS 1036379-05-1)
- 5-Amino-3-(cyanomethyl)-N-hydroxy-1H-pyrazole-4-carboximidamide (CAS 321905-55-9)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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