2-(4-Chlorobenzyl)-4-((3,4-dichlorobenzyl)thio)quinazoline CAS 303149-25-9
| CAS No. | 303149-25-9 |
| Molecular Formula | C22H15Cl3N2S |
| Molecular Weight | 445.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 445.79 g/mol gives 2-(4-Chlorobenzyl)-4-((3,4-dichlorobenzyl)thio)quinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(4-Chlorobenzyl)-4-((3,4-dichlorobenzyl)thio)quinazoline (CAS 303149-25-9), a certified reference material (molecular formula C22H15Cl3N2S, MW 445.79 g/mol) for analytical method development and quality control.
2-(4-Chlorobenzyl)-4-((3,4-dichlorobenzyl)thio)quinazoline (C22H15Cl3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Chlorobenzyl)-4-((3,4-dichlorobenzyl)thio)quinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H15Cl3N2S |
| Molecular Weight | 445.79 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
- 3'-(5-((4-Chlorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1'-phenyl-1'H-1,2'-bipyrrole (CAS 860649-78-1)
- 2-(4-Chlorobenzyl)-4-((3-(trifluoromethyl)benzyl)thio)quinazoline (CAS 303149-27-1)
- 5-(4-((2-Chlorobenzyl)oxy)phenyl)-N'-(2-hydroxybenzylidene)-1H-pyrazole-3-carbohydrazide (CAS 634897-22-6)
- (E)-2-((4-chlorobenzyl)thio)quinoline-3-carbaldehyde O-(4-methylbenzoyl) oxime (CAS 692260-11-0)
- Methyl 2-((2-((4-chlorobenzyl)thio)-6-(methoxymethyl)pyrimidin-4-yl)thio)benzoate (CAS 338748-01-9)
- 4-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-02-8)
- 2-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-22-2)
- 3-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-51-7)
Recommended Standards
- 1-((4-Bromophenyl)sulfonyl)-2-((2-chlorobenzyl)thio)-4,5-dihydro-1H-imidazole (CAS 868217-81-6)
- 2-[(3-Chlorophenyl)methyl]-4-{[(2,4-dichlorophenyl)methyl]sulfanyl}quinazoline (CAS 303149-49-7)
- 2,4,5-Triiodo-1H-imidazole (CAS 1746-25-4)
- 2-[(4-Chlorophenyl)methyl]-4-{[(2,4-dichlorophenyl)methyl]sulfanyl}quinazoline (CAS 303149-26-0)
- 6'-chloro-1',2'-dihydrospiro[azetidine-3,3'-indole]-2'-one (CAS 2167904-62-1)
- O-(4-isopropylbenzyl)hydroxylamine (CAS 706751-57-7)
- 2-[4-(2-phenoxyethoxy)phenyl]acetic acid (CAS 383134-87-0)
- 3-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]morpholine, trifluoroacetic acid (CAS 1803582-51-5)
- Methyl 4-oxo-6-(thiophen-2-yl)-4,5-dihydro-[1,2,3]triazolo[1,5-a]pyrazine-3-carboxylate (CAS 1403233-70-4)
- 2-Amino-2-methylpropane-1,3-diol hemi(4-methyl-2-oxo-2H-chromen-7-yl phosphate) (CAS 107475-10-5)
- 2-hydroxycyclopentanecarboxylic acid (CAS 81887-89-0)
- 2-Hydroxy-4,5-diphenyl-1,3,2-dioxaphospholane 2-oxide (CAS 97176-53-9)
- (Prop-2-en-1-yl)[(2,3,4-trimethoxyphenyl)methyl]amine (CAS 893575-14-9)
- 98035-79-1 Small cardioactive peptide A L-Methioninamide, L-alanyl-L-arginyl-L-prolylglycyl-L-tyrosyl-L-leucyl-L-alanyl-L-phenylalanyl-L-prolyl-L-arginyl- SCPA (CAS 98035-79-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com