2-(4-Chlorobenzyl)-4-((3-(trifluoromethyl)benzyl)thio)quinazoline CAS 303149-27-1
| CAS No. | 303149-27-1 |
| Molecular Formula | C23H16ClF3N2S |
| Molecular Weight | 444.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-(4-Chlorobenzyl)-4-((3-(trifluoromethyl)benzyl)thio)quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 2-(4-Chlorobenzyl)-4-((3-(trifluoromethyl)benzyl)thio)quinazoline (CAS 303149-27-1), a certified reference material (molecular formula C23H16ClF3N2S, MW 444.90 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, 2-(4-Chlorobenzyl)-4-((3-(trifluoromethyl)benzyl)thio)quinazoline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 444.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C23H16ClF3N2S |
| Molecular Weight | 444.90 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
- 2-(4-Chlorobenzyl)-4-((3,4-dichlorobenzyl)thio)quinazoline (CAS 303149-25-9)
- 4-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-02-8)
- 2-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-22-2)
- 3-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-51-7)
- 3-((4-Chlorobenzyl)sulfinyl)-4-ethyl-5-((3-(trifluoromethyl)phenoxy)methyl)-4H-1,2,4-triazole (CAS 956607-36-6)
- 3'-(5-((4-Chlorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1'-phenyl-1'H-1,2'-bipyrrole (CAS 860649-78-1)
- 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1-(3,4-dichlorobenzyl)-1H-pyrazole (CAS 477713-45-4)
- 4,6-Bis((2-chlorobenzyl)thio)cinnoline (CAS 6957-47-7)
Recommended Standards
- N-(4-(4-Chlorophenyl)-5-methylthiazol-2-yl)-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetamide (CAS 848341-57-1)
- Halometasone (CAS 50629-82-8)
- 4-((4-Chlorophenyl)sulfonyl)-N-(4-ethoxyphenyl)-2-(furan-2-yl)oxazol-5-amine (CAS 862794-89-6)
- Halometasone Impurity 6 (CAS CATO-C4X-14466)
- 3-ethynyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1487219-25-9)
- 6-Bromo-5-chloro-4-fluoro-1H-indazole (CAS 2417226-68-5)
- 1-(2-(Trifluoromethyl)thiazol-5-yl)ethan-1-one (CAS 1393585-05-1)
- (Cyclohexyl)dimethylmethoxysilane (CAS 54731-56-5)
- 2-(6-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)acetohydrazide (CAS 1221792-29-5)
- N-(2-Chloro-4-fluorophenyl)-2-{[3-ethyl-7-(4-methylphenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide (CAS 1040632-56-1)
- 5,10,15,20-tetrakis(p-chlorophenyl)porphyrin iron(III) chloride (CAS 36965-70-5)
- 2-Chloro-5-sulfamoylfuran-3-carboxylic acid (CAS 2138410-16-7)
- 6,7-Dimethoxy-2-methyl-1-(4-nitrophenethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 63937-57-5)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com