3-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate CAS 1144035-51-7
| CAS No. | 1144035-51-7 |
| Molecular Formula | C22H22ClN3O5 |
| Molecular Weight | 443.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 443.88 g/mol gives 3-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-51-7), molecular formula C22H22ClN3O5 and molecular weight 443.88 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (C22H22ClN3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22ClN3O5 |
| Molecular Weight | 443.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorobenzyl Standards
- 4-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-02-8)
- 2-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-22-2)
- 3-((4-Chlorobenzyl)sulfinyl)-4-ethyl-5-((3-(trifluoromethyl)phenoxy)methyl)-4H-1,2,4-triazole (CAS 956607-36-6)
- 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1-(3,4-dichlorobenzyl)-1H-pyrazole (CAS 477713-45-4)
- 4,6-Bis((2-chlorobenzyl)thio)cinnoline (CAS 6957-47-7)
- 4,6-Bis((4-chlorobenzyl)thio)cinnoline (CAS 6957-46-6)
- N-(4-chlorobenzyl)-2-((3-oxo-2-(thiophen-2-ylmethyl)isoindolin-1-yl)thio)acetamide (CAS 866008-25-5)
- 2-((2-Chlorobenzyl)thio)-6-(4-methoxyphenyl)-4-phenylnicotinonitrile (CAS 332175-72-1)
Recommended Standards
- 2-Amino-2-[5-[5-(3-chloro-4-propoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-benzofuranyl]-1,3-propanediol (CAS 1220973-37-4)
- N-[(2-Chlorophenyl)methyl]-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775308-47-8)
- N-(2-Chlorophenyl)-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775337-99-9)
- 2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-4-phenylpyridine-3-carbonitrile (CAS 860650-51-7)
- 2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-ethylphenyl)acetamide (CAS 332380-84-4)
- 2-Amino-6-bromo-5-chloronicotinic acid (CAS 2230875-16-6)
- AEE 788 D5 (CAS 1292840-54-0)
- 1-(2-(Benzyloxy)ethyl)piperidin-4-one (CAS 948894-76-6)
- Dolutegravir Impurity 24 (CAS 2315439-81-5)
- 2-Phenyl-1-(3-(trifluoromethyl)phenyl)ethan-1-one (CAS 1533-04-6)
- 6-Hydroxy-5-methylisoindolin-1-one (CAS 1138220-72-0)
- 2,4-Dichloro-1-{2-[(4-fluorophenyl)sulfanyl]ethoxy}benzene (CAS 339010-82-1)
- n-(4-(2-Oxopropyl)phenyl)acetamide (CAS 4173-84-6)
- Des-Ile12-Aib13-Tirzepatide (CAS CATO-CPTD788960)
Why CATO?
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