2-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-oxoethoxy)isoindoline-1,3-dione CAS 303150-02-9
| CAS No. | 303150-02-9 |
| Molecular Formula | C20H16ClF3N4O4 |
| Molecular Weight | 468.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 468.81 g/mol gives 2-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-oxoethoxy)isoindoline-1,3-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-oxoethoxy)isoindoline-1,3-dione (CAS 303150-02-9) is a high-purity analytical reference standard with the molecular formula C20H16ClF3N4O4 and a molecular weight of 468.81 g/mol.
2-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-oxoethoxy)isoindoline-1,3-dione (C20H16ClF3N4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16ClF3N4O4 |
| Molecular Weight | 468.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 2-[4-(4-Chloro-3-fluorophenoxy)phenyl]-6-phenyl-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 478248-04-3)
- N4-(6-Chloro-2-methoxyacridin-9-yl)-N1,N1-bis(2-chloroethyl)pentane-1,4-diamine (CAS 64046-79-3)
- 2-((4-Chloro-N-phenylphenyl)sulfonamido)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 339102-58-8)
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- Ethyl (1-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2,3-dihydro-1H-inden-2-yl)carbamate (CAS 303152-95-6)
- ((2-Chloro-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-yl)ethynyl)triisopropylsilane (CAS 2856022-05-2)
- 339105-33-8 4-[(2-chloro-1,3-thiazol-5-yl)methoxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]benzene-1-sulfonamide 8N-063 (CAS 339105-33-8)
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Recommended Standards
- 2-((4-Bromophenyl)thio)-3-((4-chlorophenyl)sulfonyl)-4,6-dimethylpyridine (CAS 478262-70-3)
- Delafloxacin impurity 33 (CAS 1620905-72-7)
- (E)-6-((4-chlorophenyl)thio)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2,4-dichlorobenzyl) oxime (CAS 339022-78-5)
- (E)-({6-[(4-chlorophenyl)sulfanyl]imidazo[2,1-b][1,3]thiazol-5-yl}methylidene)[(2,6-dichlorophenyl)methoxy]amine (CAS 339022-82-1)
- 1-(6-Aminopyridin-3-yl)ethanone hydrochloride (CAS 19828-21-8)
- 2-Hydroxybenzamidine (CAS 45744-18-1)
- Oxazolo[4,5-c]pyridine, 7-bromo-2-ethyl- (CAS 118685-69-1)
- Ethyl 2-(6-bromo-3-cyano-2-nitrophenyl)acetate (CAS 1805103-27-8)
- N-Benzyl-2-butyl-3-ethoxy-2H-indazole-6-carboxamide (CAS 919107-22-5)
- Ethyl 4-(3-hydroxyphenyl)-2-oxopyrrolidine-3-carboxylate (CAS 62253-69-4)
- N-(Dicyclopropylmethyl)-2-ethyl-3,4-dihydro-2H-pyrrol-5-amine (CAS 750561-53-6)
- 2-[1-(2,2-diethoxyethyl)-1h-1,2,3-triazol-4-yl]ethan-1-ol (CAS 915369-54-9)
- N-(4-Fluorophenyl)-2-methylbenzamide (CAS 199121-61-4)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
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