Dapagliflozin Impurity 154 CAS CATO-C4X-1138154
| CAS No. | CATO-C4X-1138154 |
| Molecular Formula | C22H28O7 |
| Molecular Weight | 404.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dapagliflozin Impurity 154.
Dapagliflozin Impurity 154 (CAS CATO-C4X-1138154) is a certified pharmaceutical impurity reference standard with the molecular formula C22H28O7 and a molecular weight of 404.45 g/mol.
Dapagliflozin Impurity 154 (C22H28O7) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dapagliflozin Impurity 154 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H28O7 |
| Molecular Weight | 404.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 34 (CAS CATO-C4X-113834)
- Dapagliflozin Impurity 108 (CAS CATO-C4X-1138108)
- Dapagliflozin Impurity 184 (CAS CATO-C4X-1138184)
- Dapagliflozin impurity 16 (CAS CATO-C4X-1138216)
- Dapagliflozin Furanose Isomer (CAS 1469910-70-0)
- Dapagliflozin Impurity N9 (CAS 2452300-81-9)
- Dapagliflozin (CAS 461432-26-8)
- Dapagliflozin Impurity 1 (CAS 1373321-04-0)
Recommended Standards
- N-[4-(4-Butylphenyl)-1,3-thiazol-2-yl]-3-(trifluoromethyl)benzamide (CAS 439111-36-1)
- N-(4-{[(5Z)-4-oxo-3-phenyl-2-[(4H-1,2,4-triazol-4-yl)imino]-1,3-thiazolidin-5-ylidene]methyl}phenyl)acetamide (CAS 478077-88-2)
- Ipragliflozin (CAS 761423-87-4)
- 1,4-O-Didesmethyl rac-Niranthin (CAS 81263-83-4)
- Cinacalcet Impurity 95 (CAS CATO-C4X-105995)
- Dopamine Impurity 34 (CAS CATO-C4X-190834)
- Avanafil Impurity 122 (CAS CATO-C4X-1118122)
- 2-Bromo-6,7-dihydroimidazo[1,2-a]pyrazin-8(5H)-one (CAS 1936039-76-7)
- 3,3'-(((Pyridin-3-ylmethylene)bis(oxy))bis(methylene))dipyridine (CAS 2761253-03-4)
- 5,6,7,8-Tetrahydroquinoline-8-carbothioamide (CAS 53400-60-5)
- Ethyl N-(2-{[3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetyl)carbamate (CAS 625376-47-8)
- 2-(3,5-Dimethylphenyl)acetic Acid (CAS 42288-46-0)
- 2-Bromo-4,5-dimethylpyridine (CAS 66533-31-1)
- Anti-TF Antigen Peptide P30-1 trifluoroacetate salt (CAS 573664-50-3)
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