3'-Chloro-3-((4-chlorobenzyl)oxy)-2-methyl-5'-(trifluoromethyl)-4H-[1,2'-bipyridin]-4-one CAS 303151-81-7
| CAS No. | 303151-81-7 |
| Molecular Formula | C19H13Cl2F3N2O2 |
| Molecular Weight | 429.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3'-Chloro-3-((4-chlorobenzyl)oxy)-2-methyl-5'-(trifluoromethyl)-4H-[1,2'-bipyridin]-4-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3'-Chloro-3-((4-chlorobenzyl)oxy)-2-methyl-5'-(trifluoromethyl)-4H-[1,2'-bipyridin]-4-one (CAS 303151-81-7) is a high-purity analytical reference standard with the molecular formula C19H13Cl2F3N2O2 and a molecular weight of 429.22 g/mol.
The molecular framework of 3'-Chloro-3-((4-chlorobenzyl)oxy)-2-methyl-5'-(trifluoromethyl)-4H-[1,2'-bipyridin]-4-one (C19H13Cl2F3N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H13Cl2F3N2O2 |
| Molecular Weight | 429.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- 1-(2-Bromophenoxy)-3-nitrodibenz[b,f][1,4]oxazepin-11(10H)-one (CAS 442631-06-3)
- Hydrido(dimethylphosphinous acid-kP)[hydrogen bis(dimethylphosphinito-kP)]platinum(II) (CAS 173416-05-2)
- Opicapone Impurity 88 (CAS CATO-C4X-240488)
- (R)-1-(2-Bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea (CAS 501951-42-4)
- n-Butyl-1,1,2,2,3,3-d6 Alcohol (CAS 1219794-84-9)
- (4,6-Dihydropyrazolo[1,5-c]thiazol-2-yl)methanol (CAS 623564-67-0)
- 3-Chloro-2-ethyltetrahydro-2H-pyran (CAS 31535-06-5)
- 5-Phenyl-2-(4-phenylthiazol-2-yl)-4-(2-(thiazol-2-yl)hydrazono)-2,4-dihydro-3H-pyrazol-3-one (CAS 314761-14-3)
- 4-Chloro-2-(chloromethyl)-1,3-benzoxazole (CAS 143708-34-3)
- tert-Butyl 3-(2-cyanoacetyl)piperidine-1-carboxylate (CAS 842112-53-2)
- 3-Chloro-6-fluoropicolinonitrile (CAS 1207609-53-7)
- 7-Cyano-2-naphthoic acid (CAS 5043-08-3)
- 5-bromo-2-[(3S)-2,6-dioxo-3-piperidyl]isoindoline-1,3-dione (CAS 1418209-88-7)
- Sperm Peptide P10G (H-2424.0001) (CAS 137353-73-2)
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