2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]-1,4-dihydronaphthalene-1,4-dione CAS 303152-84-3
| CAS No. | 303152-84-3 |
| Molecular Formula | C18H13ClF3N3O2 |
| Molecular Weight | 395.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]-1,4-dihydronaphthalene-1,4-dione.
2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]-1,4-dihydronaphthalene-1,4-dione (CAS 303152-84-3) is a high-purity analytical reference standard with the molecular formula C18H13ClF3N3O2 and a molecular weight of 395.76 g/mol.
2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]-1,4-dihydronaphthalene-1,4-dione (C18H13ClF3N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]-1,4-dihydronaphthalene-1,4-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H13ClF3N3O2 |
| Molecular Weight | 395.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- Ethyl 2-((2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoropyrimidin-4-yl)thio)acetate (CAS 1823182-35-9)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenethylpyrimidine-2,4(1H,3H)-dione (CAS 251310-60-8)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxyphenyl)-1H-pyrrole-2-carboxamide (CAS 338956-38-0)
- Methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate (CAS 298708-79-9)
- 3-{[2-chloro-6-(1H-1,2,4-triazol-1-yl)phenyl]methyl}-1-[3-(trifluoromethyl)phenyl]urea (CAS 866042-61-7)
- 2-Chloro-5-{[4-(trifluoromethoxy)phenyl]sulfamoyl}benzoic acid (CAS 745798-18-9)
- N-(4-chloro-3-nitrophenyl)-2-((4-methyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 329778-13-4)
- N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-methoxy-N-methylbenzenesulfonohydrazide (CAS 339276-30-1)
Recommended Standards
- Bay 41-4109 (CAS 298708-81-3)
- BAy 41-4109 (less active enantiomer) (CAS 476617-51-3)
- 38725-13-2 CTK4I0375 Isononanamine,N,N-diisononyl- (9CI) (CAS 38725-13-2)
- Mabuterol Impurity 11 (CAS CATO-C4X-145411)
- 5-nitroindan-2-one (CAS 116530-60-0)
- 3,4-Dibromo-1,1,1,2,2-pentafluorobutane (CAS 378-69-8)
- 1-((4-Bromophenoxy)methyl)cyclobutanecarboxylic acid (CAS 1387558-63-5)
- 2-(2,5-dichlorophenyl)[1,3]oxazolo[4,5-b]pyridine (CAS 52333-67-2)
- 1H-1,2,3-Benzotriazole-7-carboxylic Acid (CAS 62972-61-6)
- 3-(4-Bromo-1H-indol-3-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 691885-26-4)
- 4-((2-Fluorobenzyl)oxy)piperidine hydrochloride (CAS 614731-34-9)
- 2-(But-3-en-2-yloxy)isoindoline-1,3-dione (CAS 329698-13-7)
- methyl N-[4-(fluorosulfonyl)-2-nitrophenyl]carbamate (CAS 1803600-76-1)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
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