4-(Chloromethyl)-3-(2,6-dichlorophenyl)-5-methylisoxazole CAS 303225-22-1
| CAS No. | 303225-22-1 |
| Molecular Formula | C11H8Cl3NO |
| Molecular Weight | 276.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Chloromethyl)-3-(2,6-dichlorophenyl)-5-methylisoxazole (CAS 303225-22-1), molecular formula C11H8Cl3NO and molecular weight 276.55 g/mol, is a CATO reference standard with documented purity and traceability.
4-(Chloromethyl)-3-(2,6-dichlorophenyl)-5-methylisoxazole (C11H8Cl3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Chloromethyl)-3-(2,6-dichlorophenyl)-5-methylisoxazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8Cl3NO |
| Molecular Weight | 276.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
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Recommended Standards
- 2-Chloro-4-(perfluoroethyl)pyrimidine-5-carboxylic acid (CAS 954226-17-6)
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- 2,2,2-Trichloro-1-(7-methyl-1H-indol-3-yl)ethan-1-one (CAS 855628-07-8)
- N-Nitrosotris-(2-chloroethyl)urea (CAS 69113-01-5)
- 1,2,3,5-Tetramethoxybenzene (CAS 5333-45-9)
- 1-(2-(Tert-butoxy)ethyl)-1h-pyrazol-3-amine (CAS 1342613-18-6)
- Cinidon (CAS 175156-71-5)
- 1-Phenyl-3-trifluoromethyl-1H-pyrazole-4-carbonyl chloride (CAS 1003579-29-0)
- 3-(2,2-difluoroethoxy)azetidine hydrochloride (CAS 1375472-46-0)
- tert-Butyl 4-(3-chlorobenzylamino)piperidine-1- (CAS 848345-63-1)
- 2-Ethyl-2-methoxyhexan-1-amine (CAS 326487-92-7)
- (R)-3-Aminomethyl-2-Boc-3,4-dihydro-1H-isoquinoline (CAS 150417-18-8)
- 1-(4-(Difluoromethoxy)phenyl)-5-phenyl-1,3-dihydro-2H-imidazole-2-thione (CAS 1105190-29-1)
- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
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