| CAS No. | 3037703-03-7 |
| Molecular Formula | C7H4I2N2 |
| Molecular Weight | 369.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 369.93 g/mol gives Axitinib Impurity 58 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Axitinib Impurity 58 (CAS 3037703-03-7), a pharmacopoeial impurity reference standard (molecular formula C7H4I2N2, MW 369.93 g/mol) used for the identification and quantification of trace impurities in APIs.
Axitinib Impurity 58 (C7H4I2N2) contains a nitrile group, iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Axitinib Impurity 58 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
| Molecular Formula | C7H4I2N2 |
| Molecular Weight | 369.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |