6-Chloro-1-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-3-morpholinoquinoxalin-2(1H)-one CAS 303986-20-1
| CAS No. | 303986-20-1 |
| Molecular Formula | C20H18Cl2F3N5O2 |
| Molecular Weight | 488.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Chloro-1-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-3-morpholinoquinoxalin-2(1H)-one (C20H18Cl2F3N5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 6-Chloro-1-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-3-morpholinoquinoxalin-2(1H)-one (CAS 303986-20-1), a certified reference material (molecular formula C20H18Cl2F3N5O2, MW 488.29 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-1-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-3-morpholinoquinoxalin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18Cl2F3N5O2 |
| Molecular Weight | 488.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ylidene}-N-{[(4-chlorophenyl)carbamoyl]amino}acetamide (CAS 321430-53-9)
- (E)-[1-(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)ethylidene]amino N-(4-chlorophenyl)carbamate (CAS 321432-66-0)
- 3-Chloro-N-(2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethyl)-5-(trifluoromethyl)pyridin-2-amine (CAS 338792-94-2)
- 1-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}methyl)-3-(3-chloropropyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one (CAS 866019-79-6)
- N-[2-(4-Chloro-3,5-dimethylphenoxy)-5-(trifluoromethyl)phenyl]-N'-(1,2,2-trichlorovinyl)urea (CAS 218156-26-4)
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- 5-chloro-6-ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrazine-2-carboxamide (CAS 1254058-47-3)
- N-(2-Chloro-4-fluorophenyl)-2-{[3-ethyl-7-(4-methylphenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide (CAS 1040632-56-1)
Recommended Standards
- (E)-[(5-{[(2-chlorophenyl)methyl]sulfanyl}-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylidene]amino 2-chlorobenzoate (CAS 321553-56-4)
- Aripiprazole Impurity 45 (CAS CATO-C4X-100845)
- 3,5-Bis((4-bromobenzyl)thio)-1,2,4-thiadiazole (CAS 332110-09-5)
- (E)-5-((4-chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde O-(2-chlorobenzoyl) oxime (CAS 321553-49-5)
- 4-Bromo-2-((phenylamino)methyl)phenol (CAS 61593-31-5)
- 5-Chlorothiophene-2-thiol (CAS 2404-97-9)
- 5-Hydroxy-1-methyl-2,3-diazaspiro[5.5]Undec-1-en-4-one (CAS 1311254-67-7)
- 3-Butylcyclobutane-1-carboxylic acid (CAS 66016-18-0)
- 8-Bromopyrrolo[2,3,4-de]quinolin-5(4H)-one (CAS 2767589-36-4)
- 2,3-Dihydro-3-(4-methoxyphenyl)-2-thioxo-4(1H)-quinazolinone (CAS 1031-88-5)
- Bis(4-nitrobenzyl) malonate (CAS 67245-85-6)
- 4-Amino-2-(trifluoromethyl)pyrimidine-5-carbonitrile (CAS 943-25-9)
- 6-(4-Fluorophenyl)-1,2-thiazinane 1,1-dioxide (CAS 1537863-72-1)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
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