(2E)-2-(Benzenesulfonyl)-3-{3-[(2-chloro-6-fluorophenyl)methyl]-2,4-bis(propan-2-yloxy)phenyl}prop-2-enenitrile CAS 303994-45-8
| CAS No. | 303994-45-8 |
| Molecular Formula | C28H27ClFNO4S |
| Molecular Weight | 528.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (2E)-2-(Benzenesulfonyl)-3-{3-[(2-chloro-6-fluorophenyl)methyl]-2,4-bis(propan-2-yloxy)phenyl}prop-2-enenitrile (CAS 303994-45-8), a certified reference material (molecular formula C28H27ClFNO4S, MW 528.03 g/mol) for analytical method development and quality control.
(2E)-2-(Benzenesulfonyl)-3-{3-[(2-chloro-6-fluorophenyl)methyl]-2,4-bis(propan-2-yloxy)phenyl}prop-2-enenitrile (C28H27ClFNO4S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2E)-2-(Benzenesulfonyl)-3-{3-[(2-chloro-6-fluorophenyl)methyl]-2,4-bis(propan-2-yloxy)phenyl}prop-2-enenitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H27ClFNO4S |
| Molecular Weight | 528.03 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related E Standards
- Ethyl 2-[2-(benzenesulfonyl)-4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy]propanoate (CAS 338407-15-1)
- (Z)-[2-(Benzenesulfonyl)-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene][(4-chlorophenyl)methoxy]amine (CAS 672950-28-6)
- (E)-[2-(Benzenesulfonyl)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethylidene][(2,6-dichlorophenyl)methoxy]amine (CAS 338758-60-4)
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- (Z)-[2-(Benzenesulfonyl)-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene][(4-fluorophenyl)methoxy]amine (CAS 672950-32-2)
- 2-[(3AR)-1-(benzenesulfonyl)-3a-methyl-5-oxo-octahydropyrrolo[2,3-b]pyrrol-2-yl]phenyl benzenesulfonate (CAS 957029-95-7)
- N-(Benzenesulfonyl)-N-(1-benzyl-3-cyano-4,5-dimethyl-1H-pyrrol-2-yl)benzenesulfonamide (CAS 478033-05-5)
- 2-[3-(Benzenesulfonyl)-4-[(4-chlorophenyl)methoxy]phenoxy]-3-chloro-5-(trifluoromethyl)pyridine (CAS 306979-53-3)
Recommended Standards
- N-(4-(Benzyloxy)phenyl)-2-((4-(4-chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 476483-67-7)
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- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(benzyloxy)-3-chlorophenyl)propanoic acid (CAS 205181-81-3)
- N-(5-chloro-2-methoxyphenyl)-2-((5-phenyl-1-tosyl-1H-imidazol-2-yl)thio)acetamide (CAS 332155-89-2)
- 2-Bromo-N-(thiazol-2-yl)butanamide (CAS 116200-99-8)
- 2-(4-(Hexyl(methyl)amino)phenyl)-1,4-dihydroxyanthracene-9,10-dione (CAS 89132-73-0)
- [(2,3-Dichlorophenyl)methyl](propyl)amine (CAS 893586-86-2)
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- tert-Butyl 2-(furan-3-ylmethyl)hydrazinecarboxylate (CAS 150767-03-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com