Indomethacin Impurity 2 CAS 97460-20-3
| CAS No. | 97460-20-3 |
| Molecular Formula | C28H34ClN3O5 |
| Molecular Weight | 528.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Indomethacin Impurity 2 (C28H34ClN3O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Indomethacin Impurity 2 (CAS 97460-20-3) is a high-purity analytical reference standard with the molecular formula C28H34ClN3O5 and a molecular weight of 528.04 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Indomethacin Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H34ClN3O5 |
| Molecular Weight | 528.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Indomethacin Standards
- Indomethacin acyl-β-D-glucuronide (CAS 75523-11-4)
- Indomethacin 4-methoxyphenyl ester, 98% (CAS 261766-24-9)
- Indomethacin heptyl ester, >98% (CAS 282728-47-6)
- NO-Indomethacin (CAS 301838-28-8)
- Indomethacin Isopropyl Ester (CAS 72616-25-2)
- Indomethacin-D4 (CAS 87377-08-0)
- Indomethacin Impurity 1 (CAS 4584-39-8)
- Indomethacin Impurity 24 (CAS 828-94-4)
Recommended Standards
- (2E)-2-(Benzenesulfonyl)-3-{3-[(2-chloro-6-fluorophenyl)methyl]-2,4-bis(propan-2-yloxy)phenyl}prop-2-enenitrile (CAS 303994-45-8)
- N-(5-chloro-2-methoxyphenyl)-2-((5-phenyl-1-tosyl-1H-imidazol-2-yl)thio)acetamide (CAS 332155-89-2)
- N-(4-(Benzyloxy)phenyl)-2-((4-(4-chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 476483-67-7)
- 2,4,6-Tris(4-(tert-butoxy)phenyl)-1,3,5,2,4,6-trioxatriborinane (CAS 326926-57-2)
- N-[(1H-1,3-Benzodiazol-2-yl)methyl]-2,4-dichlorobenzamide (CAS 338771-69-0)
- 1-(Iodomethyl)bicyclo[2.2.1]heptane (CAS 61192-16-3)
- n-(6-(Methylsulfonyl)pyridin-3-yl)thiophene-2-carboxamide (CAS 1241265-21-3)
- 5-Bromo-n-isopropyl-2-methoxy-n-methylbenzenesulfonamide (CAS 923693-46-3)
- 2-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid hydrate (CAS 303094-23-7)
- tert-Butyl 4-((3-cyanopyridin-2-yl)oxy)piperidine-1-carboxylate (CAS 1065484-09-4)
- 2-(2-Bromo-4-formyl-6-methoxyphenoxy)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 553674-30-9)
- 2,6-Difluoroisonicotinonitrile (CAS 51991-35-6)
- N-Butyl-2-hydroxy-[1,1'-biphenyl]-3-carboxamide (CAS 131-90-8)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com