3-Chloro-6-((3-(trifluoromethyl)phenyl)sulfinyl)-[1,2,4]triazolo[4,3-b]pyridazine CAS 303996-28-3
| CAS No. | 303996-28-3 |
| Molecular Formula | C12H6ClF3N4OS |
| Molecular Weight | 346.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-6-((3-(trifluoromethyl)phenyl)sulfinyl)-[1,2,4]triazolo[4,3-b]pyridazine.
CATO supplies 3-Chloro-6-((3-(trifluoromethyl)phenyl)sulfinyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 303996-28-3), a certified reference material (molecular formula C12H6ClF3N4OS, MW 346.72 g/mol) for analytical method development and quality control.
3-Chloro-6-((3-(trifluoromethyl)phenyl)sulfinyl)-[1,2,4]triazolo[4,3-b]pyridazine (C12H6ClF3N4OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H6ClF3N4OS |
| Molecular Weight | 346.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 8-Bromo-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one (CAS 851045-03-9)
- Ethyl 3-bromo-5-fluoropyridine-4-carboxylate (CAS 1214335-25-7)
- 3-Ethyl-4-methoxyaniline (CAS 518990-49-3)
- 9,10-Dioxo-9,10-dihydroanthracene-1,5-diyl dibenzoate (CAS 575489-38-2)
- (S)-2-(tert-Butoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid (CAS 711017-85-5)
- 2,4,5-T-Methyl Ester (CAS 1928-37-6)
- (R)-Methanandamide (CAS 157182-49-5)
- Methyl 2,3-dichloro-5-fluorophenylacetate (CAS 1804880-89-4)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
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