7-Chloro-6-methoxy-2-(2-nitrophenyl)quinoline-5,8-diol CAS 61472-42-2
| CAS No. | 61472-42-2 |
| Molecular Formula | C16H11ClN2O5 |
| Molecular Weight | 346.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Chloro-6-methoxy-2-(2-nitrophenyl)quinoline-5,8-diol.
CATO supplies 7-Chloro-6-methoxy-2-(2-nitrophenyl)quinoline-5,8-diol (CAS 61472-42-2), a certified reference material (molecular formula C16H11ClN2O5, MW 346.72 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 7-Chloro-6-methoxy-2-(2-nitrophenyl)quinoline-5,8-diol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 346.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Chloro-6-methoxy-2-(2-nitrophenyl)quinoline-5,8-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11ClN2O5 |
| Molecular Weight | 346.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-[(E)-2-[(5-Chloro-2-hydroxyphenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one (CAS 320420-38-0)
- 3-Chloro-6-((3-(trifluoromethyl)phenyl)sulfinyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 303996-28-3)
- (2E)-1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-cyclopropyl-2-[(dimethylamino)methylidene]propane-1,3-dione (CAS 155376-87-7)
- 6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine (CAS 1644443-47-9)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(5-fluoro-2-methylphenyl)acetamide (CAS 439107-80-9)
- 2-Chloro-4-(methylsulfonyl)-3-((2,2,2-trifluoroethoxy)methyl)benzoic acid (CAS 120100-77-8)
- 5-Chloro-2-(4-fluorophenyl)-4-(4-methoxyphenoxy)pyridazin-3(2H)-one (CAS 478049-35-3)
- 2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetonitrile (CAS 860786-19-2)
Recommended Standards
- 3-((Dimethyl(vinyl)silyl)oxy)-1,1,3,5,5-pentamethyl-1,5-divinyltrisiloxane (CAS 60111-52-6)
- Bromodiiodomethane (CAS 557-95-9)
- 2-((3-(4-Chlorophenoxy)-4-oxo-4h-chromen-7-yl)oxy)acetic acid (CAS 315234-25-4)
- ((2R,3R,4R,5R)-3-Acetoxy-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate (CAS 10190-39-3)
- 1-(4-Fluorophenyl)-N-methyl-4-nitro-1H-pyrazol-5-amine (CAS 318238-08-3)
- (2,5-Difluorophenyl)(5-methylpyridin-2-yl)methanone (CAS 1187164-75-5)
- 3-Methyl-4-nitro-isothiazole-5-carbonitrile (CAS 4577-00-8)
- 5-(4-Methoxyphenyl)-1h-pyrrole-2-carboxylic acid (CAS 149769-78-8)
- 2,5-Dichloroquinoline-3-carbaldehyde (CAS 1064137-50-3)
- 3-(Piperidin-1-yl)propane-1,2-diol (CAS 4847-93-2)
- 5-Bromoquinazolin-4-ol (CAS 147006-47-1)
- 2-Chloro-1-(2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one (CAS 22178-82-1)
- Levetiracetam Impurity 24 (CAS 79194-54-0)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
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