(Z)-3-((2-chloroacetoxy)imino)-1-(3-(trifluoromethyl)benzyl)indolin-2-one CAS 303996-88-5
| CAS No. | 303996-88-5 |
| Molecular Formula | C18H12ClF3N2O3 |
| Molecular Weight | 396.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (Z)-3-((2-chloroacetoxy)imino)-1-(3-(trifluoromethyl)benzyl)indolin-2-one.
CATO supplies (Z)-3-((2-chloroacetoxy)imino)-1-(3-(trifluoromethyl)benzyl)indolin-2-one (CAS 303996-88-5), a certified reference material (molecular formula C18H12ClF3N2O3, MW 396.75 g/mol) for analytical method development and quality control.
(Z)-3-((2-chloroacetoxy)imino)-1-(3-(trifluoromethyl)benzyl)indolin-2-one (C18H12ClF3N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (Z)-3-((2-chloroacetoxy)imino)-1-(3-(trifluoromethyl)benzyl)indolin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H12ClF3N2O3 |
| Molecular Weight | 396.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
- (Z)-3-((2-chloroacetoxy)imino)-1-(4-methylbenzyl)indolin-2-one (CAS 303149-28-2)
- 3-Chloroacetoxy-2-naphthoicacidanilide (CAS 84522-14-5)
- N-(2-Chloroacetoxy)-2-(quinolin-8-yloxy)acetimidamide (CAS 88757-14-6)
- 4-(Chloroacetoxy)butyl acrylate (CAS 157525-13-8)
- N-(Chloroacetoxy)succinimide (CAS 27243-15-8)
- 2-(2-chloroacetoxy)acetic acid (CAS 30450-82-9)
Recommended Standards
- (2E)-3-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]-2-cyanobut-2-enamide (CAS 303153-06-2)
- [(3Z)-5-Chloro-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino acetate (CAS 477864-51-0)
- (S)-2-((4-Chloro-6-((4-nitrophenyl)amino)-1,3,5-triazin-2-yl)amino)pentanedioic acid (CAS 61955-61-1)
- [1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methyl N-[3-(trifluoromethyl)phenyl]carbamate (CAS 338419-13-9)
- 3-Nitroquinolin-2(1H)-one (CAS 103029-75-0)
- (2S,3S)-3-((1H-imidazol-1-yl)methyl)tetrahydrofuran-2-carboxylic acid (CAS 1820580-03-7)
- D-Norleucine (CAS 327-56-0)
- 3-Amino-7-nitro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1h)-one (CAS 1375474-50-2)
- 2-(2,5-Dimethoxyphenyl)azepane (CAS 383130-85-6)
- 5-Bromo-2-deoxycytidine (CAS 1022-79-3)
- 3-Chloro-4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-carboxylic acid (CAS 175202-23-0)
- Hyoscine EP Impurity A (CAS 4684-28-0)
- 6,7-Dimethoxy-1-(4-nitrophenyl)isochromane (CAS 92774-40-8)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
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