4-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)vinyl)pyrimidin-2-amine CAS 303997-62-8
| CAS No. | 303997-62-8 |
| Molecular Formula | C12H8ClF3N4 |
| Molecular Weight | 300.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)vinyl)pyrimidin-2-amine (CAS 303997-62-8), molecular formula C12H8ClF3N4 and molecular weight 300.67 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H8ClF3N4, 4-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)vinyl)pyrimidin-2-amine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 300.67 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)vinyl)pyrimidin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8ClF3N4 |
| Molecular Weight | 300.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
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- 2-Pyridinecarbaldehyde N-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]hydrazone (CAS 173213-31-5)
- 3-(2-Chlorobenzoyl)-4-hydroxy-2H-1-benzopyran-2-one (CAS 181938-56-7)
- N-Carbamimidoyl-N-methylglycine hemi-2-hydroxysuccinic acid salt (CAS 686351-75-7)
- 3-Chloro-6-(4-ethylpiperazin-1-yl)pyridazine (CAS 939598-19-3)
- N-tert-Butyl-4-{[2-oxo-5-(trifluoromethyl)-1,2-dihydropyridin-1-yl]methyl}benzamide (CAS 339025-07-9)
- 3-(Hydroxyamino)-1-methylpyrrolidine-2,5-dione (CAS 399044-16-7)
- 3,4,5,6-Tetra-O-acetyl myo-Inositol (CAS 90366-30-6)
- (4-bromooxazol-2-yl)-triisopropyl-silane (CAS 2167710-98-5)
- Methyl (E)-2-(methoxyimino)-2-(o-tolyl)acetate (CAS 120974-97-2)
- 1-(4-Isopropoxyphenyl)pentan-2-one (CAS 88795-90-8)
- Fosfomycin Trometamol Enantiomer 1 AND 2Mixture (CAS CATO-C4X-131632)
- Neuropeptide S (rat) (CAS 412938-75-1)
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