3-Chloro-2-[(E)-2-[(pyridin-4-yl)methylidene]hydrazin-1-yl]-5-(trifluoromethyl)pyridine CAS 338795-33-8
| CAS No. | 338795-33-8 |
| Molecular Formula | C12H8ClF3N4 |
| Molecular Weight | 300.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Chloro-2-[(E)-2-[(pyridin-4-yl)methylidene]hydrazin-1-yl]-5-(trifluoromethyl)pyridine (CAS 338795-33-8), molecular formula C12H8ClF3N4 and molecular weight 300.67 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H8ClF3N4, 3-Chloro-2-[(E)-2-[(pyridin-4-yl)methylidene]hydrazin-1-yl]-5-(trifluoromethyl)pyridine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 300.67 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-Chloro-2-[(E)-2-[(pyridin-4-yl)methylidene]hydrazin-1-yl]-5-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClF3N4 |
| Molecular Weight | 300.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 2-[4-(3-chloro-4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetic acid (CAS 1152513-96-6)
- (E)-3-chloro-2-(2-(pyridin-3-ylmethylene)hydrazinyl)-5-(trifluoromethyl)pyridine (CAS 339099-61-5)
- 4-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)vinyl)pyrimidin-2-amine (CAS 303997-62-8)
- 2-Chloro-N-(2-(trifluoromethyl)phenyl)isonicotinamide (CAS 1040055-59-1)
- 4-Chloro-4'-(trifluoromethyl)biphenyl-3-carboxylic acid (CAS 1179847-52-9)
- 2-Chloro-4-(2-trifluoromethylphenyl)benzoic acid (CAS 1237080-49-7)
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Recommended Standards
- 2-Pyridinecarbaldehyde N-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]hydrazone (CAS 173213-31-5)
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- 3-(Benzo[d][1,3]dioxol-5-yl)-6-chloro-2H-chromen-2-one (CAS 163130-52-7)
- N4-[3-(trifluoromethyl)phenyl]-2-chloroisonicotinamide (CAS 680217-42-9)
- (4-Morpholinopyridin-2-yl)methanamine (CAS 1249267-08-0)
- (2S,3S)-2,3-dimethyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-carboxylic acid (CAS 2412578-19-7)
- 2-(4-Bromo-2-fluorophenyl)-3-methylpyridine (CAS 1187169-99-8)
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- Dibenzo(A,C)Anthracene (CAS 215-58-7)
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- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
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