Ivabradine Impurity 49 CAS 304464-98-0（free base）
| CAS No. | 304464-98-0（free base） |
| Molecular Formula | C26H34N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Ivabradine Impurity 49 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 491.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Ivabradine Impurity 49 (CAS 304464-98-0（free base）), a pharmacopoeial impurity reference standard (molecular formula C26H34N2O5HCl, MW 491.03 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ivabradine Impurity 49 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H34N2O5 HCl |
| Molecular Weight | 491.03 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ivabradine Standards
- Ivabradine Impurity 25 HCl (CAS 1132079-01-6)
- Ivabradine impurity 90 (CAS 1132667-04-9)
- Ivabradine Impurity 9 (CAS 1204612-29-2)
- Ivabradine Impurity 28 (CAS 1206230-28-5)
- Ivabradine-d3 Hydrochloride (CAS 1217809-61-4)
- Ivabradine impurity 86 (CAS 1220993-44-1)
- Ivabradine Impurity 20 (CAS 1235547-06-4)
- Ivabradine Impurity 21 (CAS 1235547-07-5)
Recommended Standards
- Penicillin Impurity 44 (CAS CATO-C4X-189944)
- Tegoprazan Impurity 76 (CAS CATO-C4X-229776)
- Cefixime Impurity 62 (CAS CATO-C4X-113962)
- 4-[(3-propyl-1,2,4-oxadiazol-5-yl)methyl]piperidine hydrochloride (CAS 1909305-95-8)
- 2-amino-5-methoxy-3-methylbenzoic acid (CAS 1180497-46-4)
- 5-(4-((3-Fluorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine (CAS 1706448-66-9)
- 2-(((3,4-Difluorophenyl)amino)methyl)-6-methoxyphenol (CAS 864420-98-4)
- Ethyl 1-(piperidin-3-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 2120805-13-0)
- 2-Chloro-6-(thiophen-3-yl)pyrazine (CAS 426829-59-6)
- Mast Cell Degranulating Peptide HR-1 (CAS 80533-94-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com