Ivabradine Impurity 9 CAS 1204612-29-2
| CAS No. | 1204612-29-2 |
| Molecular Formula | C12H17NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 243.73 g/mol gives Ivabradine Impurity 9 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ivabradine Impurity 9 (CAS 1204612-29-2) is a certified pharmaceutical impurity reference standard with the molecular formula C12H17NO2HCl and a molecular weight of 243.73 g/mol.
Structurally, Ivabradine Impurity 9 (C12H17NO2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 243.73 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ivabradine Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17NO2 HCl |
| Molecular Weight | 243.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ivabradine Standards
- Ivabradine Impurity 25 HCl (CAS 1132079-01-6)
- Ivabradine impurity 90 (CAS 1132667-04-9)
- Ivabradine Impurity 28 (CAS 1206230-28-5)
- Ivabradine-d3 Hydrochloride (CAS 1217809-61-4)
- Ivabradine impurity 86 (CAS 1220993-44-1)
- Ivabradine Impurity 20 (CAS 1235547-06-4)
- Ivabradine Impurity 21 (CAS 1235547-07-5)
- Ivabradine Impurity 4 (CAS 1246638-08-3)
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- (R)-Benzyl 3-methylpiperazine-1-carboxylate hydrochloride (CAS 1217831-52-1)
- 2,5-Bis(prop-2-yn-1-yloxy)terephthalohydrazide (CAS 2564821-81-2)
- Adrenal Peptide E, bovine (CAS 78355-50-7)
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