Oxytetracycline EP Impurity B Hydrate CAS 305833-60-7
| CAS No. | 305833-60-7 |
| Molecular Formula | C22H24N2O8 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Oxytetracycline EP Impurity B Hydrate (CAS 305833-60-7), a pharmacopoeial impurity reference standard (molecular formula C22H24N2O8H2O, MW 462.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Oxytetracycline EP Impurity B Hydrate (C22H24N2O8H2O) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 462.45 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Oxytetracycline EP Impurity B Hydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O8 H2O |
| Molecular Weight | 462.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Oxytetracycline Standards
- Oxytetracycline EP Impurity A (CAS 14206-58-7)
- Oxytetracycline Hemicalcium Salt (CAS 15251-48-6)
- Oxytetracycline EP Impurity D (CAS 18695-01-7)
- Oxytetracycline EP Impurity E (CAS 18751-99-0)
- Oxytetracycline Hydrochloride (CAS 2058-46-0)
- Oxytetracycline EP impurity F(Anhydrooxytetracycline) (CAS 4660-26-8)
- Oxytetracycline EP Impurity B (CAS 60-54-8)
- Oxytetracycline Dihydrate (CAS 6153-64-6)
Recommended Standards
- Trametinib impurity 04 (CAS 871700-25-3)
- Cetrorelix Impurity 26 (CAS CATO-C4X-201426)
- Lefamulinum Impurity 31 (CAS CATO-C4X-304731)
- 4-(3,5-Dioxothiomorpholino)-2-hydroxybutanoic acid (CAS 1697292-46-8)
- 2-{[(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)methyl]amino}-5-methylbenzoic acid (CAS 959579-16-9)
- 6-Imino-1-methyl-1,6-dihydropyrimidin-4-amine (CAS 99419-02-0)
- 2-Aminoheptanoic acid (CAS 1115-90-8)
- 2-chloro-6-methyl-thieno[3,2-d]pyrimidine (CAS 2033057-21-3)
- 3-(1-Methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-propionic acid (CAS 149287-38-7)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com