Nintedanib Esylate Hemihydrate CAS 3059992-86-5
| CAS No. | 3059992-86-5 |
| Molecular Formula | 2*C31H33N5O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Nintedanib Esylate Hemihydrate (CAS 3059992-86-5) is a high-purity analytical reference standard with the molecular formula C31H33N5O4C2H6O3SH2O and a molecular weight of 667.78 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Nintedanib Esylate Hemihydrate is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 667.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Nintedanib Esylate Hemihydrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 2*C31H33N5O4 2*C2H6O3S H2O |
| Molecular Weight | 667.78 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Nintedanib Standards
- Nintedanib Impurity 158 (CAS 1023942-14-4)
- Nintedanib Impurity 9 (CAS 1038972-16-5)
- Nintedanib Impurity 156 (CAS 1040320-04-4)
- Nintedanib Impurity 19 (CAS 1125-88-8)
- Nintedanib Impurity 6 (CAS 1139453-98-7)
- Nintedanib Impurity N24 (CAS 1139455-52-9)
- Nintedanib Impurity N10 (CAS 1139457-10-5)
- Nintedanib Impurity N8 (CAS 1139458-48-2)
Recommended Standards
- Methyl 6-Chloro-2-methylnicotinate (CAS 851759-19-8)
- Tert-butyl (R)-3-amino-3-(hydroxymethyl)piperidine-1-carboxylate (CAS 2165517-36-0)
- 4-Bromo-2-hydroxypyridine (CAS 36953-37-4)
- 4-Cyano-3-(difluoromethyl)-2-methylpyridine-6-methanol (CAS 1807160-60-6)
- 2-Amino-N-((3-methoxypyrazin-2-yl)methyl)-N-methylacetamide (CAS 1353983-40-0)
- 4-chloro-6-nitropyrrolo[2,1-f][1,2,4]triazine (CAS 1160995-37-8)
- 2,6-Dimethoxy-4-[(propylamino)methyl]phenol (CAS 735240-64-9)
- 2-((1-(4-(3-Chlorothiophen-2-yl)-6-methylpyrimidin-2-yl)-1H-pyrrol-2-yl)methylene)malononitrile (CAS 861210-73-3)
- 2-(4-Amino-3,5-dimethyl-1h-pyrazol-1-yl)-N-isopropylacetamide (CAS 1152696-09-7)
- Semaglutide Impurity 246 (CAS CATO-C4X-2226246)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com