Rivaroxaban Impurity 159 CAS 3069765-41-6
| CAS No. | 3069765-41-6 |
| Molecular Formula | C19H19ClN4O7S |
| Molecular Weight | 482.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Rivaroxaban Impurity 159 (CAS 3069765-41-6), a pharmacopoeial impurity reference standard (molecular formula C19H19ClN4O7S, MW 482.89 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H19ClN4O7S, Rivaroxaban Impurity 159 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 482.89 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H19ClN4O7S |
| Molecular Weight | 482.89 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 184 (CAS CATO-C4X-1090184)
- Rivaroxaban Impurity 158 (CAS CATO-C4X-1090158)
- Rivaroxaban Impurity 98 (CAS CATO-C4X-109098)
- Rivaroxaban Impurity 86 (CAS CATO-C4X-109086)
- Rivaroxaban Impurity N8 (CAS 1770812-38-8)
- Rivaroxaban EP Impurity H (CAS 1770812-37-7)
- Rivaroxaban Impurity 200 (CAS CATO-C4X-1090200)
- Rivaroxaban Impurity 26 (CAS CATO-C4X-109026)
Recommended Standards
- 3-((4-Bromobenzyl)thio)-5-(((4-chlorobenzyl)thio)methyl)-4-isopropyl-4H-1,2,4-triazole (CAS 344268-27-5)
- N-allyl-6-(((4-chlorophenyl)thio)methyl)-2-((3,4-dichlorobenzyl)thio)pyrimidin-4-amine (CAS 478261-64-2)
- N-Nitroso Cloxacillin Impurity 33 (CAS CATO-C4X-159733)
- Tivozanib Impurity 13 (CAS CATO-C4X-340013)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
- Brexpiprazole impurity 72 (CAS CATO-C4X-113172)
- Indometacin EP Impurity B (CAS 2882-15-7)
- 5-Bromo-4-ethoxy-2,3-difluorobenzoic acid (CAS 2404734-29-6)
- Ethylboronic Acid Pinacol Ester (CAS 82954-89-0)
- (2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-carbonitrile (CAS 121123-91-9)
- (1R,2R)-2-(thietan-3-ylamino)cyclohexan-1-ol (CAS 1867924-53-5)
- N-(Benzo[d]thiazol-2-yl)-2-(4-methyl-6-oxopyrimidin-1(6H)-yl)acetamide (CAS 1203032-05-6)
- ((2R,3S,4S,5S,6S)-3-acetoxy-5,6-diacetyl-4,5,6-trihydroxytetrahydro-2H-pyran-2-yl)methyl acetate (CAS 27086-14-2)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
Why CATO?
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