Orforglipron impurity 35 CAS 7254-19-5
| CAS No. | 7254-19-5 |
| Molecular Formula | C9H6BrNO2 |
| Molecular Weight | 240.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Orforglipron impurity 35 (CAS 7254-19-5), a pharmacopoeial impurity reference standard (molecular formula C9H6BrNO2, MW 240.05 g/mol) used for the identification and quantification of trace impurities in APIs.
Orforglipron impurity 35 (C9H6BrNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Orforglipron impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6BrNO2 |
| Molecular Weight | 240.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Orforglipron Standards
- Orforglipron impurity 22 (CAS 3047293-07-9)
- Orforglipron Impurity 40 (CAS CATO-C4X-323440)
- Orforglipron Impurity 53 (CAS CATO-C4X-323453)
- Orforglipron impurity 127 (CAS 2203400-61-5)
- Orforglipron impurity 140 (CAS 757247-91-9)
- Orforglipron impurity 136 (CAS 2274775-42-5)
- Orforglipron impurity 33 (CAS CATO-C4X-323433)
- Orforglipron impurity 27 (CAS 465529-57-1)
Recommended Standards
- Methyl 5-bromo-2-cyanobenzoate (CAS 714237-95-3)
- 4-(3-Bromophenyl)-4H-1,2,4-triazol-3-ol (CAS 1007578-99-5)
- Methyl 3-Bromo-5-cyanobenzoate (CAS 453566-15-9)
- (4'-Acetyl-[1,1'-biphenyl]-4-yl)boronic acid (CAS 1029438-14-9)
- Ethinylestradiol 2-Hydroxy Impurity (CAS 50394-89-3)
- Promethazine Impurity 37 (CAS CATO-C4X-141837)
- Dorzolamide Hydrochloride EP Impurity C (CAS CATO-C4X-122816)
- 4-((Trimethylsilyl)ethynyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1015609-91-2)
- 5-chloro-2-methyl-thiazolo[5,4-b]pyridine (CAS 109202-21-3)
- 3,4-Difluoro-2-methoxybenzoic acid (CAS 875664-52-1)
- 2-(Benzyloxy)-5-(trifluoromethyl)benzoic acid (CAS 53985-54-9)
- Bosutinib Impurity 26 (CAS 67669-19-6)
- 7-[1-(4-Methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 477865-11-5)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com