Cefmetazole Impurity 48 CAS 310466-38-7
| CAS No. | 310466-38-7 |
| Molecular Formula | C8H5FS |
| Molecular Weight | 152.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Cefmetazole Impurity 48 (CAS 310466-38-7, C8H5FS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to sulfur-containing functionality, fluorine substitution, an aromatic ring system, Cefmetazole Impurity 48 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 152.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H5FS |
| Molecular Weight | 152.19 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Cefmetazole Standards
- Cefmetazole Impurity 21 (CAS 52069-55-3)
- Cefmetazole Impurity 58 (CAS CATO-C4X-150758)
- Cefmetazole Impurity 11 (CAS 55817-29-3)
- Cefmetazole Impurity 31 (CAS 55862-52-7)
- Cefmetazole Impurity 46 (CAS 17347-32-9)
- Cefmetazole Impurity 47 (CAS 4923-87-9)
- Cefmetazole Impurity 20 (Chloroacetonitrile) (CAS 107-14-2)
- Cefmetazole impurity 75 (CAS 62671-38-9)
Recommended Standards
- Dapoxetine Impurity 86 (CAS 103548-16-9)
- Tiotropium Bromide Impurity 32 (CAS 1570-95-2)
- Rivastigmine EP Impurity G (CAS 23308-82-9)
- Betahistine impurity 33 (CAS 13585-92-7)
- Amodiaquine Impurity 2 (CAS 79049-30-2)
- Sivelestat Impurity 7 (CAS 1071827-84-3)
- Isavuconazole Impurity 237 (CAS 60695-12-7)
- 3-Bromo-N,N-diethyl-5-methylbenzenesulfonamide (CAS 1020252-94-1)
- 2-Amino-4-fluoro-5-morpholinobenzoic acid (CAS 1033778-63-0)
- 2-Bromo-1-chloro-4-(difluoromethoxy)benzene (CAS 1000574-90-2)
- 3,6-Dihydro-2H-[1,4]dioxino[2,3-f]indole-7-carboxylic Acid (CAS 59820-87-0)
- [4-(Chloromethyl)phenyl]-phenylmethanone (CAS 42728-62-1)
- 4-Chloro-5-fluoro-pyridine-3-carbaldehyde hydrochloride (CAS 2121514-41-6)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
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