Paliperidone Impurity 156 CAS 3109322-10-0
| CAS No. | 3109322-10-0 |
| Molecular Formula | C9H11BrFNO |
| Molecular Weight | 248.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Paliperidone Impurity 156 (CAS 3109322-10-0), a pharmacopoeial impurity reference standard (molecular formula C9H11BrFNO, MW 248.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Paliperidone Impurity 156 (C9H11BrFNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Paliperidone Impurity 156 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11BrFNO |
| Molecular Weight | 248.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Paliperidone Standards
- Paliperidone USP Related Compound C (CAS 130049-82-0)
- Paliperidone Impurity 154 (CAS CATO-C4X-1724154)
- Paliperidone Impurity 161 (CAS 1160611-32-4)
- Paliperidone Impurity 67 (CAS CATO-C4X-172467)
- Paliperidone Impurity 155 (CAS CATO-C4X-1724155)
- Paliperidone Impurity 61 (CAS 1138463-56-5)
- Paliperidone Impurity 56 (CAS CATO-C4X-172456)
- Paliperidone Impurity 58 (CAS CATO-C4X-172458)
Recommended Standards
- N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)formamide (CAS 2096336-53-5)
- 1-bromo-4-methoxy-2-nitrobenzene 10079-53-5 (CAS 10079-53-5)
- 5-(2,4-Dichlorophenyl)-1,3,4-oxathiazol-2-one (CAS 23589-75-5)
- 5-bromo-1,3-dihydrobenzo[c]isothiazole 2,2-dioxide (CAS 111248-92-1)
- Ubidecarenone (Coenzyme Q10) EP Impurity C (Mixture of Isomers) (CAS CATO-C4X-13767)
- Vildagliptin Impurity 114 (R-Isomer) (CAS CATO-C4X-1100114)
- Palbociclib Impurity 98 (CAS 2340184-77-0)
- (3-Phenoxybenzyl)hydrazine (CAS 85293-11-4)
- 5-Chloro-2-cyclopropylpyrimidine (CAS 89622-78-6)
- 4-Methyl-N-{5-methyl-10-oxo-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl}benzamide (CAS 223261-54-9)
- 4-[(1-Methyl-1h-imidazol-2-yl)sulfanyl]piperidine hydrochloride (CAS 1177344-02-3)
- (s)-2-Amino-2-(2,3,4,5-tetrafluorophenyl)ethan-1-ol (CAS 1213482-97-3)
- 4-(Imidazo[1,2-a]pyrazin-2-yl)-1,2,5-oxadiazol-3-amine (CAS 1031927-02-2)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com