Paliperidone Impurity 67 CAS CATO-C4X-172467
| CAS No. | CATO-C4X-172467 |
| Molecular Formula | C12H15ClN2O2 |
| Molecular Weight | 254.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Paliperidone Impurity 67 (CAS CATO-C4X-172467) is a certified pharmaceutical impurity reference standard with the molecular formula C12H15ClN2O2 and a molecular weight of 254.71 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Paliperidone Impurity 67 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 254.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H15ClN2O2 |
| Molecular Weight | 254.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Paliperidone Standards
- Paliperidone Impurity 161 (CAS 1160611-32-4)
- Paliperidone Impurity 154 (CAS CATO-C4X-1724154)
- Paliperidone Impurity 155 (CAS CATO-C4X-1724155)
- Paliperidone Impurity 163 (CAS CATO-C4X-1724163)
- Paliperidone Impurity 156 (CAS 3109322-10-0)
- Paliperidone Impurity 151 (CAS CATO-C4X-1724151)
- Paliperidone USP Related Compound C (CAS 130049-82-0)
- Paliperidone Impurity 36 (CAS CATO-C4X-1724136)
Recommended Standards
- Lornoxicam impurity 69 (CAS CATO-C4X-201669)
- Glycopyrrolate Impurity 3 (CAS 92021-41-5)
- Bilastine Impurity 10 (CAS 1638785-19-9)
- N-(7-chloronaphthalen-1-yl)pyridin-4-amine (CAS CATO-C3D-262362)
- Olaparib Impurity 117 (CAS CATO-C4X-1135117)
- Ibrutinib Impurity 158 (CAS CATO-C4X-1064158)
- Orlistat Impurity 14 (CAS 130793-26-9)
- 4,4＇-Methylenebis(2,6-di-tert-butylphenol) (CAS 118-82-1)
- 3-(Aminomethyl)-3-(3,4-dichlorophenyl)cyclobutan-1-ol (CAS 1498073-46-3)
- 5-(4-Iodophenyl)nicotinaldehyde (CAS 887973-86-6)
- 2-Chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)acetamide (CAS 182123-52-0)
- Xanthanoic acid (CAS 82-07-5)
- 2,3-Difluoro-4-(trifluoromethyl)benzyl bromide (CAS 213203-85-1)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
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