2-(Trifluoromethyl)benzoyl Chloride CAS 312-94-7
| CAS No. | 312-94-7 |
| Molecular Formula | C8H4ClF3O |
| Molecular Weight | 208.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(Trifluoromethyl)benzoyl Chloride (C8H4ClF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(Trifluoromethyl)benzoyl Chloride (CAS 312-94-7), molecular formula C8H4ClF3O and molecular weight 208.56 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Trifluoromethyl)benzoyl Chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4ClF3O |
| Molecular Weight | 208.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Trifluoromethyl Standards
- 3-Methyl-4-(trifluoromethyl)benzyl chloride (CAS 1261679-44-0)
- 2-Methyl-4-(trifluoromethyl)benzyl chloride (CAS 888739-69-3)
- (1-Trifluoromethyl-pentyl)cyclopentane (CAS 1099598-17-0)
- 1-Butyl-4-trifluoromethyl-cyclohexane (CAS 1349717-21-0)
- 8-Methyl-3-(trifluoromethyl)-8-azabicyclo[3.2.1]octan-3-amine (CAS 1341551-33-4)
- 3′-(trifluoromethyl)propiophenone (CAS 1533-03-5)
- (4-(Trifluoromethyl)bicyclo[2.2.2]Octan-1-yl)methanol (CAS 94994-14-6)
- (5-((Trifluoromethyl)thio)pyridin-3-yl)methanamine (CAS 1204234-24-1)
Recommended Standards
- 1-(3-Chloro-4-fluorophenyl)-2,2-difluoroethan-1-one (CAS 1352223-06-3)
- 2,4,6-Trifluoro-benzeneacetyl ChlorideDISCONTINUED, offer stable T793535 (CAS 714963-55-0)
- 2-Chloro-2,2-difluoro-1-(3-fluorophenyl)ethan-1-one (CAS 1352222-12-8)
- 2’-Chloro-2,2,2-trifluoroacetophenone (CAS 5860-95-7)
- 2-Bromo-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole hydrochloride (CAS 1621525-67-4)
- 3-Bromo-2-(difluoromethyl)-6-methylpyridin-4-amine (CAS 1806056-25-6)
- 3-(3,4-Dimethoxyphenyl)-1H-pyrazol-5(4H)-one (CAS 264208-47-1)
- 1,5-Dimethyl-1H-pyrazole-4-carboxamide (CAS 103589-70-4)
- 1-Propylazepan-2-one (CAS 52644-85-6)
- 2-(4-Isopropylphenyl)cyclohexan-1-ol (CAS 197704-79-3)
- (6-(Furan-2-yl)pyridin-3-yl)boronic acid (CAS 2225177-92-2)
- Benzyl(1-(3-chlorophenyl)-3-(pyrrolidin-1-yl)propyl)(methyl)carbamate (CAS 675602-81-0)
- Ondansetron Impurity 5 (CAS 1432682-04-6)
- Semaglutide Impurity 1(OtBu-Ste-D-γGlu(OtBu)-AEEA-AEEA-OH) (CAS CATO-C4X-22261)
Why CATO?
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